EP 1238114 A2 20020911 - METHODS AND COMPOSITIONS RELATING TO ELECTRICAL DETECTION OF NUCLEIC ACID REACTIONS
Title (en)
METHODS AND COMPOSITIONS RELATING TO ELECTRICAL DETECTION OF NUCLEIC ACID REACTIONS
Title (de)
METHODE UND ZUSAMMENSETZUNGEN FÜR DEN ELEKTRISCHEN NACHWEIS VON NUKLEINESÄURE REAKTIONEN
Title (fr)
PROCEDES ET COMPOSITIONS SE RAPPORTANT A LA DETECTION ELECTRIQUE DES REACTIONS D'ACIDES NUCLEIQUES
Publication
Application
Priority
- US 0033497 W 20001211
- US 45850199 A 19991209
- US 45853399 A 19991209
- US 45968599 A 19991213
Abstract (en)
[origin: WO0142508A2] This invention relates to the detection of molecular interactions between biological molecules. Specifically, the invention relates to electrical detection of interactions such as hybridization between nucleic acids or peptide antigen-antibody interactions using arrays of peptides or oligonucleotides. In particular, the invention relates to an apparatus and methods for detecting nucleic acid hybridization or peptide binding using electronic methods including AC impedance. In some embodiments, no electrochemical or other label moieties are used. In others, electrochemically active labels are used to detect reactions on hydrogel arrays, including genotyping reactions such as the single base extension reaction.
IPC 1-7
IPC 8 full level
C12M 1/00 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 27/00 (2006.01); G01N 27/02 (2006.01); G01N 27/416 (2006.01); G01N 31/22 (2006.01); G01N 33/483 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 37/00 (2006.01)
CPC (source: EP)
G01N 33/5438 (2013.01); C12Q 1/6825 (2013.01)
Citation (search report)
See references of WO 0142508A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0142508 A2 20010614; WO 0142508 A3 20020314; WO 0142508 A9 20020530; AU 2907201 A 20010618; CA 2393733 A1 20010614; EP 1238114 A2 20020911; JP 2003516165 A 20030513
DOCDB simple family (application)
US 0033497 W 20001211; AU 2907201 A 20001211; CA 2393733 A 20001211; EP 00993326 A 20001211; JP 2001544379 A 20001211