Global Patent Index - EP 1239846 A2

EP 1239846 A2 20020918 - TRANSDERMAL ADMINISTRATION OF PHENYLPROPANOLAMINE

Title (en)

TRANSDERMAL ADMINISTRATION OF PHENYLPROPANOLAMINE

Title (de)

TRANSDERMALE VERABREICHUNG VON PHENYLPROPANOLAMIN

Title (fr)

ADMINISTRATION TRANSDERMIQUE DE PHENYLPROPANOLAMINE

Publication

EP 1239846 A2 20020918 (EN)

Application

EP 00990223 A 20001215

Priority

  • US 0034091 W 20001215
  • US 46509899 A 19991216
  • US 60789200 A 20000630
  • US 73839300 A 20001214
  • US 73841000 A 20001214

Abstract (en)

[origin: WO0143734A2] Methods and systems are provided for the transdermal administration of racemic phenylpropanolamine, i.e., a mixture of two or more of the four isomers of phenylpropanolamine, (+)-norephedrine, (-)-norephedrine, (+)-norpseudoephedrine, and (-)-norpseudoephedrine. Generally, the racemate will be a mixture of (+)-norephedrine and (-)-norephedrine. The racemic drug is administered along with a permeation enhancer. The permeation enhancer is preferably a basic compound, and optimally is a hydroxide-releasing agent such as sodium hydroxide.

IPC 1-7

A61K 9/70; A61K 47/02; A61K 31/315

IPC 8 full level

A61K 9/06 (2006.01); A61K 9/08 (2006.01); A61K 9/107 (2006.01); A61K 9/70 (2006.01); A61K 31/137 (2006.01); A61K 47/02 (2006.01); A61K 47/30 (2006.01); A61K 47/46 (2006.01); A61P 9/00 (2006.01); A61P 11/02 (2006.01)

CPC (source: EP)

A61K 9/7053 (2013.01); A61K 31/137 (2013.01); A61P 9/00 (2017.12); A61P 11/02 (2017.12)

Citation (search report)

See references of WO 0143734A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0143734 A2 20010621; WO 0143734 A3 20020103; AU 2727801 A 20010625; CA 2395289 A1 20010621; EP 1239846 A2 20020918; JP 2003528045 A 20030924

DOCDB simple family (application)

US 0034091 W 20001215; AU 2727801 A 20001215; CA 2395289 A 20001215; EP 00990223 A 20001215; JP 2001544673 A 20001215