Global Patent Index - EP 1239846 A2

EP 1239846 A2 2002-09-18 - TRANSDERMAL ADMINISTRATION OF PHENYLPROPANOLAMINE

Title (en)

TRANSDERMAL ADMINISTRATION OF PHENYLPROPANOLAMINE

Title (de)

TRANSDERMALE VERABREICHUNG VON PHENYLPROPANOLAMIN

Title (fr)

ADMINISTRATION TRANSDERMIQUE DE PHENYLPROPANOLAMINE

Publication

EP 1239846 A2 (EN)

Application

EP 00990223 A

Priority

  • US 0034091 W
  • US 46509899 A
  • US 60789200 A
  • US 73839300 A
  • US 73841000 A

Abstract (en)

[origin: WO0143734A2] Methods and systems are provided for the transdermal administration of racemic phenylpropanolamine, i.e., a mixture of two or more of the four isomers of phenylpropanolamine, (+)-norephedrine, (-)-norephedrine, (+)-norpseudoephedrine, and (-)-norpseudoephedrine. Generally, the racemate will be a mixture of (+)-norephedrine and (-)-norephedrine. The racemic drug is administered along with a permeation enhancer. The permeation enhancer is preferably a basic compound, and optimally is a hydroxide-releasing agent such as sodium hydroxide.

IPC 1-7 (main, further and additional classification)

A61K 9/70; A61K 31/315; A61K 47/02

IPC 8 full level (invention and additional information)

A61K 9/06 (2006.01); A61K 9/08 (2006.01); A61K 9/107 (2006.01); A61K 9/70 (2006.01); A61K 31/137 (2006.01); A61K 47/02 (2006.01); A61K 47/30 (2006.01); A61K 47/46 (2006.01); A61P 9/00 (2006.01); A61P 11/02 (2006.01)

CPC (invention and additional information)

A61K 9/7053 (2013.01); A61K 31/137 (2013.01)

Citation (search report)

See references of WO 0143734A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0143734 A2 20010621; WO 0143734 A3 20020103; AU 2727801 A 20010625; CA 2395289 A1 20010621; EP 1239846 A2 20020918; JP 2003528045 A 20030924

INPADOC legal status


2004-08-04 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20040123

2003-10-29 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030912

2002-11-27 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: HSU, TSUNG-MIN

2002-11-27 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: MACY, RUSSELL

2002-11-27 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: LUO, ERIC, C.

2002-09-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020716

2002-09-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI