EP 1239922 A2 20020918 - TREATMENT OF EXCESSIVE BONE OR CARTILAGE LOSS WITH AN ACTIVATOR OF ROR ALPHA AND ASSAY FOR IDENTIFYING SUCH ACTIVATOR

Title (en)

TREATMENT OF EXCESSIVE BONE OR CARTILAGE LOSS WITH AN ACTIVATOR OF ROR ALPHA AND ASSAY FOR IDENTIFYING SUCH ACTIVATOR

Title (de)

BEHANDLUNG VON ÜBERMÄSSIGEM KNOCHEN- ODER KNORPELVERLUST DURCH EINEN ROR ALPHA-AKTIVATOR UND EIN TESTVERFAHREN ZUR IDENTIFIZIERUNG DESSELBEN

Title (fr)

PROCEDE DE DOSAGE

Publication

EP 1239922 A2 20020918 (EN)

Application

EP 00972703 A 20001009

Priority

EP 0009883 W 20001009
GB 9924057 A 19991011

Abstract (en)

[origin: WO0126737A2] A method for the identification of a compound having bone growth promoting activity comprising contacting a test compound with a biological system which comprises a functional ROR alpha receptor and which is capable of generating a detectable signal in response to activation of the ROR alpha receptor by a compound having bone growth promoting activity, and monitoring the system for the generation of the signal and the use of such compounds for the prophylaxis or treatment of diseases or medical conditions which involve excessive bone or cartilage loss.

IPC 1-7

A61P 19/02; A61P 19/10; A61K 45/00; G01N 33/566

IPC 8 full level

G01N 33/50 (2006.01); A61K 45/00 (2006.01); A61P 1/02 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); G01N 33/15 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

A61P 1/02 (2017.12); A61P 19/00 (2017.12); A61P 19/02 (2017.12); A61P 19/08 (2017.12); A61P 19/10 (2017.12); G01N 33/566 (2013.01); G01N 33/6887 (2013.01); G01N 2333/70567 (2013.01); G01N 2500/00 (2013.01); G01N 2800/105 (2013.01)

Citation (search report)

See references of WO 0126737A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0126737 A2 20010419; WO 0126737 A3 20011018; AU 1134601 A 20010423; EP 1239922 A2 20020918; GB 9924057 D0 19991215; JP 2003511426 A 20030325

DOCDB simple family (application)

EP 0009883 W 20001009; AU 1134601 A 20001009; EP 00972703 A 20001009; GB 9924057 A 19991011; JP 2001529798 A 20001009