EP 1240311 A1 20020918 - DNA MOLECULES ENCODING HUMAN NHL, A DNA HELICASE
Title (en)
DNA MOLECULES ENCODING HUMAN NHL, A DNA HELICASE
Title (de)
DIE MENSCHLICHE DNA-HELICASE NHL KODIERENDE DNA-MOLEKÜLE
Title (fr)
MOLECULES D'ADN CODANT LA NHL HUMAINE, UNE HELICASE D'ADN
Publication
Application
Priority
- US 0033065 W 20001207
- US 16997099 P 19991209
Abstract (en)
[origin: WO0142434A1] The present invention disclosed isolated nucleic acid molecules (polynucleotides) which encode NHL, a putative DNA helicase. The present invention in turn relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding NHL, substantially purified forms of associated NHL, associated mutant proteins, and methods associated with identifying compounds which modulate NHL, which will be useful in the treatment of various neoplastic disorders. Both a genomic clone containing regulatory and intron sequences, as well as the exon structure and open reading frame of human NHL are disclosed.
IPC 1-7
C12N 9/00; C12N 9/10; C12N 1/20; C12N 15/00; C07H 21/02; C07H 21/04
IPC 8 full level
C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/90 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
C12N 9/90 (2013.01)
Citation (search report)
See references of WO 0142434A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0142434 A1 20010614; CA 2395378 A1 20010614; EP 1240311 A1 20020918; JP 2003523181 A 20030805
DOCDB simple family (application)
US 0033065 W 20001207; CA 2395378 A 20001207; EP 00983952 A 20001207; JP 2001544311 A 20001207