Global Patent Index - EP 1240311 A1

EP 1240311 A1 2002-09-18 - DNA MOLECULES ENCODING HUMAN NHL, A DNA HELICASE

Title (en)

DNA MOLECULES ENCODING HUMAN NHL, A DNA HELICASE

Title (de)

DIE MENSCHLICHE DNA-HELICASE NHL KODIERENDE DNA-MOLEKÜLE

Title (fr)

MOLECULES D'ADN CODANT LA NHL HUMAINE, UNE HELICASE D'ADN

Publication

EP 1240311 A1 (EN)

Application

EP 00983952 A

Priority

  • US 0033065 W
  • US 16997099 P

Abstract (en)

[origin: WO0142434A1] The present invention disclosed isolated nucleic acid molecules (polynucleotides) which encode NHL, a putative DNA helicase. The present invention in turn relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding NHL, substantially purified forms of associated NHL, associated mutant proteins, and methods associated with identifying compounds which modulate NHL, which will be useful in the treatment of various neoplastic disorders. Both a genomic clone containing regulatory and intron sequences, as well as the exon structure and open reading frame of human NHL are disclosed.

IPC 1-7 (main, further and additional classification)

C12N 9/00; C07H 21/02; C07H 21/04; C12N 1/20; C12N 9/10; C12N 15/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/90 (2006.01)

CPC (invention and additional information)

C12N 9/90 (2013.01)

Citation (search report)

See references of WO 0142434A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0142434 A1 20010614; CA 2395378 A1 20010614; EP 1240311 A1 20020918; JP 2003523181 A 20030805

INPADOC legal status


2003-11-26 [18W] APPLICATION WITHDRAWN

- Effective date: 20030924

2002-09-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020709

2002-09-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI