Global Patent Index - EP 1240354 A2

EP 1240354 A2 2002-09-18 - SINGLE NUCLEOTIDE POLYMORPHISMS IN GENES

Title (en)

SINGLE NUCLEOTIDE POLYMORPHISMS IN GENES

Title (de)

EINZELNUKLEOTIDPOLYMORPHISMEN IN GENEN

Title (fr)

POLYMORPHISMES A NUCLEOTIDE UNIQUE DES GENES

Publication

EP 1240354 A2 (EN)

Application

EP 00959964 A

Priority

  • US 0024503 W
  • US 15335799 P
  • US 22094700 P
  • US 22572400 P

Abstract (en)

[origin: WO0118250A2] The invention provides nucleic acid segments of the human genome, particularly nucleic acid segments from a gene, including polymorphic sites. Allele-specific primers and probes hybridizing to regions flanking or containing these sites are also provided. The nucleic acids, primers and probes are used in applications such as phenotype correlations, forensics, paternity testing, medicine and genetic analysis. A role for the thrombospondin gene(s) in vascular disease is also disclosed. Use of single nucleotide polymorphisms in the thrombospondin gene(s) for diagnosis, prediction of clinical course and treatment response, development of therapeutics and development of cell-culture-based and animal models for research and treatment are disclosed.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; C07K 14/47

IPC 8 full level (invention and additional information)

C07K 14/78 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6883 (2013.01); C07K 14/78 (2013.01); C12Q 2600/156 (2013.01)

Citation (search report)

See references of WO 0118250A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0118250 A2 20010315; WO 0118250 A3 20020725; AU 7119400 A 20010410; EP 1240354 A2 20020918

INPADOC legal status


2006-09-27 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20060404

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: LANDER, ERIC, S.

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: GARGILL, MICHELE

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: IRELAND, JAMES, S.

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: BOLK, STACEY

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: DALEY, GEORGE, Q.

2003-03-19 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: MCCARTHY, JEANETTE, J.

2002-09-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020319

2002-09-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE