Global Patent Index - EP 1240527 A2

EP 1240527 A2 2002-09-18 - METHOD FOR DETERMINING THE BIOLOGICALLY EFFECTIVE PARATHYROID HORMONE ACTIVITY IN A SAMPLE

Title (en)

METHOD FOR DETERMINING THE BIOLOGICALLY EFFECTIVE PARATHYROID HORMONE ACTIVITY IN A SAMPLE

Title (de)

VERFAHREN ZUR BESTIMMUNG DER PARATHORMON-AKTIVITÄT IN EINER MENSCHLICHEN PROBE

Title (fr)

PROCEDE DE DETERMINATION DE L'ACTIVITE DE PARATHORMONE BIOLOGIQUEMENT ACTIVE DANS UN ECHANTILLON

Publication

EP 1240527 A2 (DE)

Application

EP 00989994 A

Priority

  • DE 19961350 A
  • EP 0012911 W

Abstract (en)

[origin: WO0144818A2] The invention relates to an immunoassay for determining the parathyroid hormone activity in a sample and to a method for diagnosing, finding the causes for and treating disorders of the calcium metabolism, osteopathies and hyper- or hypoparathyreoses. The parathyroid hormone activity is measured by means of an antibody that binds to an epitope in the area of the receptor binding structure 15 to 22 of the parathyroid hormone, and an antibody that recognizes whether the aminoterminal end 1 to 3 of the parathyroid hormone has remained intact. The inventive assay allows taking into account the antagonist properties of some parathyroid hormone fragments.

IPC 1-7 (main, further and additional classification)

G01N 33/78; C07K 14/635; C07K 16/26

IPC 8 full level (invention and additional information)

G01N 33/78 (2006.01)

CPC (invention and additional information)

G01N 33/78 (2013.01); G01N 2333/635 (2013.01)

Citation (search report)

See references of WO 0144818A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0144818 A2 20010621; WO 0144818 A3 20020411; AU 2674601 A 20010625; DE 19961350 A1 20010621; EP 1240527 A2 20020918; US 2003175802 A1 20030918; US 2011003311 A1 20110106; US 7851163 B2 20101214

INPADOC legal status


2007-11-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20071024

2002-09-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020710

2002-09-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI