Global Patent Index - EP 1241934 A1

EP 1241934 A1 2002-09-25 - MELANOCORTIN-4 RECEPTOR DEFICIENT CELLS, NON-HUMAN TRANSGENIC ANIMALS AND METHODS OF SELECTING COMPOUNDS WHICH REGULATE BODY WEIGHT

Title (en)

MELANOCORTIN-4 RECEPTOR DEFICIENT CELLS, NON-HUMAN TRANSGENIC ANIMALS AND METHODS OF SELECTING COMPOUNDS WHICH REGULATE BODY WEIGHT

Title (de)

ZELLEN MIT DEFIZIENTEM MELANOCORTIN-4-REZEPTOR, NICHT-MENSCHLICHE TRANSGENE TIERE UND VERFAHREN ZUR AUSWAHL VON SUBSTANZEN, DIE DAS KÖRPERGEWICHT REGULIEREN KÖNNEN

Title (fr)

CELLULES DEFICIENTES EN RECEPTEURS 4 DE MELANOCORTINE, ANIMAUX TRANSGENIQUES NON HUMAINS ET PROCEDES DE SELECTION DE COMPOSES QUI REGULENT LE POIDS CORPOREL

Publication

EP 1241934 A1 (EN)

Application

EP 00980352 A

Priority

  • US 0031061 W
  • US 16507499 P

Abstract (en)

[origin: WO0133956A1] Cells and non-human transgenic animals have been engineered to be deficient in the gene encoding the melcanocortin-4 receptor protein (MC-4R). These MC-4R deficient transgenic animals can be used to select for and test potential modulators of MC-4R. This data allows for methods of screening for preferential MC-4R modulators which effect body weight through modulation of both metabolic rate and food intake, as well as associated methods of treating various disorders associated with inappropriate regulation of body weight.

IPC 1-7 (main, further and additional classification)

A01K 67/00; C12N 5/06; C12N 5/10; C12N 15/00; C12N 15/85; C12N 15/86; C12Q 1/00

IPC 8 full level (invention and additional information)

A01K 67/027 (2006.01); C07K 14/72 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01); C12Q 1/02 (2006.01)

CPC (invention and additional information)

A01K 67/0276 (2013.01); C07K 14/723 (2013.01); C12N 15/8509 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A01K 2217/20 (2013.01); A01K 2227/105 (2013.01); A01K 2227/50 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0362 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0133956 A1 20010517; CA 2390740 A1 20010517; EP 1241934 A1 20020925; EP 1241934 A4 20050427; JP 2003525596 A 20030902

INPADOC legal status


2006-03-15 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20050906

2005-06-08 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050425

2005-04-27 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20050311

2002-09-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020612

2002-09-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR