EP 1242377 A1 20020925 - A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES
Title (en)
A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES
Title (de)
EIN VERFAHREN FÜR DIE REGIOSELECTIVE SYNTHESE VON 2,2-DIALKYL-4-SUBSTITUIERTEN PIPERIDINEN
Title (fr)
PROCEDE DESTINE A LA SYNTHESE STEREOSELECTIVE DE PIPERIDINES 2,2-DIALKYL-4-SUBSTITUEES
Publication
Application
Priority
- US 0032424 W 20001206
- US 17272299 P 19991220
Abstract (en)
[origin: WO0146142A1] The present invention provides a process for preparing a compound of formula (I): wherein R<1> and R<2> each independently represent C1-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R<->M<+> wherein M<+> is a suitable cation.
IPC 1-7
IPC 8 full level
C07D 211/12 (2006.01); C07D 409/04 (2006.01)
CPC (source: EP)
C07D 211/12 (2013.01); C07D 409/04 (2013.01)
Citation (search report)
See references of WO 0146142A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0146142 A1 20010628; AU 1930601 A 20010703; EP 1242377 A1 20020925
DOCDB simple family (application)
US 0032424 W 20001206; AU 1930601 A 20001206; EP 00982250 A 20001206