Global Patent Index - EP 1242377 A1

EP 1242377 A1 2002-09-25 - A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES

Title (en)

A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES

Title (de)

EIN VERFAHREN FÜR DIE REGIOSELECTIVE SYNTHESE VON 2,2-DIALKYL-4-SUBSTITUIERTEN PIPERIDINEN

Title (fr)

PROCEDE DESTINE A LA SYNTHESE STEREOSELECTIVE DE PIPERIDINES 2,2-DIALKYL-4-SUBSTITUEES

Publication

EP 1242377 A1 (EN)

Application

EP 00982250 A

Priority

  • US 0032424 W
  • US 17272299 P

Abstract (en)

[origin: WO0146142A1] The present invention provides a process for preparing a compound of formula (I): wherein R<1> and R<2> each independently represent C1-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R<->M<+> wherein M<+> is a suitable cation.

IPC 1-7 (main, further and additional classification)

C07D 211/12; C07D 211/22; C07D 409/04

IPC 8 full level (invention and additional information)

C07D 211/12 (2006.01); C07D 409/04 (2006.01)

CPC (invention and additional information)

C07D 409/04 (2013.01); C07D 211/12 (2013.01)

Citation (search report)

See references of WO 0146142A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0146142 A1 20010628; AU 1930601 A 20010703; EP 1242377 A1 20020925

INPADOC legal status


2009-12-23 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20090701

2009-05-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20090428

2002-09-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020722

2002-09-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI