EP 1242381 A2 20020925 - 2-PHENYL-QUINOLINE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE THEREOF
Title (en)
2-PHENYL-QUINOLINE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE THEREOF
Title (de)
2-PHENYLCHINOLINDERIVATE UND DEREN VERWENDUNG ALS KONTRAKTIONSMITTEL GLATTER MUSKELZELLEN
Title (fr)
DERIVES DE 2-PHENYL-QUINOLEINE ET LEUR UTILISATION EN TANT QU'AGENT CONTRACTANT DES MUSCLES LISSES
Publication
Application
Priority
- FR 0003537 W 20001214
- FR 9915934 A 19991217
Abstract (en)
[origin: WO0144197A2] The invention concerns compounds of general formula (I) wherein: A represents a hydrogen atom or a hydroxy; B represents a hydrogen atom or a C1-C3 alkyl group; R1 represents a phenyl optionally substituted with a halogen, a hydroxy, a C1-C3 alkoxy, C1-C3 alkyl, C1-C3 fluoroalkyl or C1-C2 perfluoroalkyl group; R2, R3 and R6, identical or different, represent each a hydrogen atom, a halogen, a C1-C6 alkyl, C2-C6 alkenyl group; R4 and R5, identical or different, represent each a hydrogen atom, a C1-C6 alkyl, C2-C6 alkenyl, C3-C6 cycloalkyl group, or R4 and R5 together form a C2-C6 alkylene, C3-C6 alkenylene chain to form with the nitrogen whereto they are bound a heterocycle, said heterocycle being optionally substituted with a C1-C4 alkyl group. The invention has therapeutic applications.
IPC 1-7
IPC 8 full level
A61K 31/47 (2006.01); A61P 1/00 (2006.01); A61P 9/14 (2006.01); A61P 11/02 (2006.01); A61P 13/02 (2006.01); A61P 25/06 (2006.01); C07D 215/14 (2006.01)
CPC (source: EP US)
A61P 1/00 (2017.12 - EP); A61P 9/14 (2017.12 - EP); A61P 11/02 (2017.12 - EP); A61P 13/02 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 19/00 (2017.12 - EP); A61P 25/06 (2017.12 - EP); C07D 215/14 (2013.01 - EP US)
Citation (search report)
See references of WO 0144197A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0144197 A2 20010621; WO 0144197 A3 20020404; AU 2526001 A 20010625; EP 1242381 A2 20020925; FR 2802532 A1 20010622; JP 2003516969 A 20030520; US 2003097000 A1 20030522
DOCDB simple family (application)
FR 0003537 W 20001214; AU 2526001 A 20001214; EP 00988917 A 20001214; FR 9915934 A 19991217; JP 2001544687 A 20001214; US 14984002 A 20020614