Global Patent Index - EP 1242381 A2

EP 1242381 A2 2002-09-25 - 2-PHENYL-QUINOLINE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE THEREOF

Title (en)

2-PHENYL-QUINOLINE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE THEREOF

Title (de)

2-PHENYLCHINOLINDERIVATE UND DEREN VERWENDUNG ALS KONTRAKTIONSMITTEL GLATTER MUSKELZELLEN

Title (fr)

DERIVES DE 2-PHENYL-QUINOLEINE ET LEUR UTILISATION EN TANT QU'AGENT CONTRACTANT DES MUSCLES LISSES

Publication

EP 1242381 A2 (FR)

Application

EP 00988917 A

Priority

  • FR 0003537 W
  • FR 9915934 A

Abstract (en)

[origin: WO0144197A2] The invention concerns compounds of general formula (I) wherein: A represents a hydrogen atom or a hydroxy; B represents a hydrogen atom or a C1-C3 alkyl group; R1 represents a phenyl optionally substituted with a halogen, a hydroxy, a C1-C3 alkoxy, C1-C3 alkyl, C1-C3 fluoroalkyl or C1-C2 perfluoroalkyl group; R2, R3 and R6, identical or different, represent each a hydrogen atom, a halogen, a C1-C6 alkyl, C2-C6 alkenyl group; R4 and R5, identical or different, represent each a hydrogen atom, a C1-C6 alkyl, C2-C6 alkenyl, C3-C6 cycloalkyl group, or R4 and R5 together form a C2-C6 alkylene, C3-C6 alkenylene chain to form with the nitrogen whereto they are bound a heterocycle, said heterocycle being optionally substituted with a C1-C4 alkyl group. The invention has therapeutic applications.

IPC 1-7 (main, further and additional classification)

C07D 215/14; A61K 31/47; A61P 19/00

IPC 8 full level (invention and additional information)

A61K 31/47 (2006.01); A61P 1/00 (2006.01); A61P 9/14 (2006.01); A61P 11/02 (2006.01); A61P 13/02 (2006.01); A61P 25/06 (2006.01); C07D 215/14 (2006.01)

CPC (invention and additional information)

C07D 215/14 (2013.01)

Citation (search report)

See references of WO 0144197A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0144197 A2 20010621; WO 0144197 A3 20020404; AU 2526001 A 20010625; EP 1242381 A2 20020925; FR 2802532 A1 20010622; JP 2003516969 A 20030520; US 2003097000 A1 20030522

INPADOC legal status


2004-03-24 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20030926

2003-04-23 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030310

2002-12-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20021004

2002-09-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI