Global Patent Index - EP 1242458 A2

EP 1242458 A2 2002-09-25 - BRAIN SPECIFIC BINDING MEMBERS

Title (en)

BRAIN SPECIFIC BINDING MEMBERS

Title (de)

GEHIRN-SPEZIFISCHE BINDUNGSMOLEKÜLE

Title (fr)

ELEMENTS DE LIAISON SPECIFIQUES DU CERVEAU

Publication

EP 1242458 A2 (EN)

Application

EP 00979747 A

Priority

  • GB 0004501 W
  • US 17059999 P

Abstract (en)

[origin: WO0144300A2] The present invention relates to specific binding members directed to the brain, including specific binding members able to pass through the blood brain barrier or which are directed to areas of brain inflammation or blood brain barrier breakdown. Panels and mixtures of antibodies are provided, also individual antibody molecules and VH and VL domains, along with methods of obtaining specific binding members by selection, e.g. using libraries displayed on the surface of filamentous bacteriophage.

IPC 1-7 (main, further and additional classification)

C07K 16/18; C07K 16/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 39/395 (2006.01); A61P 9/00 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/20 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01)

CPC (invention and additional information)

C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01)

Citation (search report)

See references of WO 0144300A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family

WO 0144300 A2 20010621; WO 0144300 A3 20020613; AU 1713901 A 20010625; AU 770115 B2 20040212; CA 2393292 A1 20010621; EP 1242458 A2 20020925; JP 2003516745 A 20030520