EP 1242458 A2 20020925 - BRAIN SPECIFIC BINDING MEMBERS
Title (en)
BRAIN SPECIFIC BINDING MEMBERS
Title (de)
GEHIRN-SPEZIFISCHE BINDUNGSMOLEKÜLE
Title (fr)
ELEMENTS DE LIAISON SPECIFIQUES DU CERVEAU
Publication
Application
Priority
- GB 0004501 W 20001127
- US 17059999 P 19991213
Abstract (en)
[origin: WO0144300A2] The present invention relates to specific binding members directed to the brain, including specific binding members able to pass through the blood brain barrier or which are directed to areas of brain inflammation or blood brain barrier breakdown. Panels and mixtures of antibodies are provided, also individual antibody molecules and VH and VL domains, along with methods of obtaining specific binding members by selection, e.g. using libraries displayed on the surface of filamentous bacteriophage.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); A61P 9/00 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/20 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 25/00 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/20 (2017.12); A61P 25/28 (2017.12); A61P 35/00 (2017.12); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01)
Citation (search report)
See references of WO 0144300A2
Citation (examination)
EP 0773441 A1 19970514 - JOLLA CANCER RES FOUND [US]
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0144300 A2 20010621; WO 0144300 A3 20020613; AU 1713901 A 20010625; AU 770115 B2 20040212; CA 2393292 A1 20010621; EP 1242458 A2 20020925; JP 2003516745 A 20030520
DOCDB simple family (application)
GB 0004501 W 20001127; AU 1713901 A 20001127; CA 2393292 A 20001127; EP 00979747 A 20001127; JP 2001544787 A 20001127