EP 1242579 A2 20020925 - TH1 SPECIFIC CD4 T CELL LINES AND METHOD FOR INDUCING THEM EX VIVO
Title (en)
TH1 SPECIFIC CD4 T CELL LINES AND METHOD FOR INDUCING THEM EX VIVO
Title (de)
TH1-SPEZIFICHE T CD4-ZELLLINIEN UND EX VIVO INDUKTIONSVERFAHREN DAVON
Title (fr)
LIGNEES DE LYMPHOCYTES T CD4 SPECIFIQUES DE TYPE TH1 ET PROCEDE POUR LEUR INDUCTION EX VIVO
Publication
Application
Priority
- FR 0003708 W 20001228
- FR 9916716 A 19991230
Abstract (en)
[origin: FR2803307A1] A TH1 specific CD4 T cell line, inducing an efficient CD8 response against an infection caused by an infectious agent, is obtained by removing from a donor a biological sample containing T cells; isolating the CD4<+> T cells from said sample; simultaneously providing dendritic cells isolated from the same sample or another sample derived from the same donor; subjecting the previously isolated CD4<+> T cells to <i>in vitro</i> immunisation with a peptide of a protein of the infectious agent exhibiting at least a T epitope, in the presence of the previously obtained dendritic cells; performing at least a restimulation, in the same conditions as for immunisation, optionally substituting the dendritic cells with B cells from the same donor.
IPC 1-7
IPC 8 full level
A61P 31/00 (2006.01); A61P 33/00 (2006.01); C12N 5/02 (2006.01); C12N 5/0783 (2010.01)
CPC (source: EP US)
A61K 39/4611 (2023.05 - EP); A61K 39/464838 (2023.05 - EP); A61P 31/00 (2018.01 - EP); A61P 31/16 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 33/00 (2018.01 - EP); A61P 33/12 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C12N 5/0636 (2013.01 - EP US); A61K 2039/5158 (2013.01 - US); A61K 2039/57 (2013.01 - EP US); A61K 2239/38 (2023.05 - EP); C12N 2502/11 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
FR 2803307 A1 20010706; AU 2860901 A 20010716; EP 1242579 A2 20020925; US 2003138409 A1 20030724; WO 0149821 A2 20010712; WO 0149821 A3 20011220
DOCDB simple family (application)
FR 9916716 A 19991230; AU 2860901 A 20001228; EP 00993724 A 20001228; FR 0003708 W 20001228; US 16943502 A 20021118