Global Patent Index - EP 1242579 A2

EP 1242579 A2 2002-09-25 - TH1 SPECIFIC CD4 T CELL LINES AND METHOD FOR INDUCING THEM EX VIVO

Title (en)

TH1 SPECIFIC CD4 T CELL LINES AND METHOD FOR INDUCING THEM EX VIVO

Title (de)

TH1-SPEZIFICHE T CD4-ZELLLINIEN UND EX VIVO INDUKTIONSVERFAHREN DAVON

Title (fr)

LIGNEES DE LYMPHOCYTES T CD4 SPECIFIQUES DE TYPE TH1 ET PROCEDE POUR LEUR INDUCTION EX VIVO

Publication

EP 1242579 A2 (FR)

Application

EP 00993724 A

Priority

  • FR 0003708 W
  • FR 9916716 A

Abstract (en)

[origin: FR2803307A1] A TH1 specific CD4 T cell line, inducing an efficient CD8 response against an infection caused by an infectious agent, is obtained by removing from a donor a biological sample containing T cells; isolating the CD4<+> T cells from said sample; simultaneously providing dendritic cells isolated from the same sample or another sample derived from the same donor; subjecting the previously isolated CD4<+> T cells to <i>in vitro</i> immunisation with a peptide of a protein of the infectious agent exhibiting at least a T epitope, in the presence of the previously obtained dendritic cells; performing at least a restimulation, in the same conditions as for immunisation, optionally substituting the dendritic cells with B cells from the same donor.

IPC 1-7 (main, further and additional classification)

C12N 5/08; A61P 31/18; A61P 37/04

IPC 8 full level (invention and additional information)

A61P 31/00 (2006.01); A61P 33/00 (2006.01); C12N 5/02 (2006.01); C12N 5/0783 (2010.01)

CPC (invention and additional information)

C12N 5/0636 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/57 (2013.01); C12N 2502/11 (2013.01)

Citation (search report)

See references of WO 0149821A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

FR 2803307 A1 20010706; AU 2860901 A 20010716; EP 1242579 A2 20020925; US 2003138409 A1 20030724; WO 0149821 A2 20010712; WO 0149821 A3 20011220

INPADOC legal status


2006-10-04 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20060411

2003-07-16 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030602

2002-09-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020627

2002-09-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI