Title (en)

COMPOUNDS FOR IMMUNOTHERAPY AND DIAGNOSIS OF COLON CANCER AND METHODS FOR THEIR USE

Title (de)

VERBINDUNGEN FÜR DIE IMMUNTHERAPIE UND DIAGNOSE VON DARMKREBS UND VERFAHREN ZU DEREN VERWENDUNG

Title (fr)

COMPOSES POUR L'IMMUNOTHERAPIE ET LE DIAGNOSTIC DU CANCER DU COLON ET PROCEDES D'UTILISATION

Publication

EP 1242598 A2 20020925 (EN)

Application

EP 00989592 A 20001229

Priority

• US 0035596 W 20001229
• US 47629699 A 19991230
• US 48032100 A 20000110
• US 50462900 A 20000215
• US 51944400 A 20000306
• US 57525100 A 20000519
• US 60944800 A 20000629
• US 64981100 A 20000828

Abstract (en)

[origin: WO0149716A2] Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.

IPC 1-7

C12N 15/12; C12N 15/62; C07K 14/47; C07K 16/14; C12Q 1/68; G01N 33/53; G01N 33/574; A61K 39/00; A61K 39/395; A61P 35/00

IPC 8 full level

C07K 14/47 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP)

A61P 35/00 (2018.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); Y02A 90/10 (2018.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0149716 A2 20010712; WO 0149716 A3 20020131; AU 2608201 A 20010716; CA 2396036 A1 20010712; EP 1242598 A2 20020925

DOCDB simple family (application)

US 0035596 W 20001229; AU 2608201 A 20001229; CA 2396036 A 20001229; EP 00989592 A 20001229