EP 1246821 A2 20021009 - PROCESS FOR THE PREPARATION OF PAROXETINE AND SYNTHETIC INTERMEDITATES THEREOF
Title (en)
PROCESS FOR THE PREPARATION OF PAROXETINE AND SYNTHETIC INTERMEDITATES THEREOF
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PAROXETINE UND ZWISCHENPRODUKTEN
Title (fr)
PROCEDE DE PRODUCTION DE PAROXETINE ET SON PRODUIT INTERMEDIAIRE
Publication
Application
Priority
- GB 0002638 W 20000707
- GB 9916187 A 19990709
Abstract (en)
[origin: WO0104113A2] The present invention relates to a new process for preparing pharmaceutically active compounds and intermediates therefor. The (-) <i>trans</i> isomer of 4-(4'-fluorophenyl)-3-(3'',4''-methylenedioxyphenoxymethyl)piperidine(paroxetine) is an important compound having antidepressant and anti-Parkinson properties. This compound is used in therapy as the hydrochloride salt to treat inter alia depression, obsessive compulsive disorder (OCD) and panic. There is described herein an improved process for its preparation which avoids several isolation and purification steps required in the prior art.
IPC 1-7
IPC 8 full level
A61K 31/4525 (2006.01); A61P 3/04 (2006.01); A61P 17/14 (2006.01); A61P 25/06 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 25/30 (2006.01); A61P 25/32 (2006.01); C07D 405/12 (2006.01)
CPC (source: EP)
A61P 3/04 (2017.12); A61P 17/14 (2017.12); A61P 25/06 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 25/30 (2017.12); A61P 25/32 (2017.12); C07D 405/12 (2013.01)
Citation (search report)
See references of WO 0104113A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0104113 A2 20010118; WO 0104113 A3 20010712; AU 5995900 A 20010130; EP 1246821 A2 20021009; GB 9916187 D0 19990908; JP 2003504365 A 20030204
DOCDB simple family (application)
GB 0002638 W 20000707; AU 5995900 A 20000707; EP 00946071 A 20000707; GB 9916187 A 19990709; JP 2001509723 A 20000707