EP 1247531 A2 20021009 - TNF-derived peptides for use in treating oedema
Title (en)
TNF-derived peptides for use in treating oedema
Title (de)
TNF-Peptide zur Behandlung von Ödemen
Title (fr)
Peptides TNF-dérivés pour le traitement des oedèmes
Publication
Application
Priority
- EP 02077274 A 19990810
- EP 99942835 A 19990810
- EP 98870180 A 19980814
- EP 98870198 A 19980918
- EP 98870222 A 19981021
Abstract (en)
The present invention relates to the finding that peptides derived from a spccific domain of tumor necrosis factor-alpha (TNF- alpha ) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF- alpha from Ser<100> to Glu<116> to treat pulmonary oedema. Moreover, the present invention concerns a circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC which is very efficient in inducing oedema resorption.
IPC 1-7
IPC 8 full level
A61K 38/19 (2006.01); A61K 38/00 (2006.01); A61P 3/00 (2006.01); A61P 7/10 (2006.01); A61P 11/00 (2006.01); A61P 43/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/525 (2006.01)
IPC 8 main group level
CPC (source: EP US)
A61K 38/191 (2013.01 - EP US); A61P 3/00 (2018.01 - EP); A61P 7/00 (2018.01 - EP); A61P 7/10 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/525 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0009149 A1 20000224; AT E374039 T1 20071015; AT E395072 T1 20080515; AU 5620999 A 20000306; AU 764992 B2 20030904; BR 9912899 A 20010508; CA 2334941 A1 20000224; CA 2334941 C 20110809; CN 1181886 C 20041229; CN 1312724 A 20010912; CZ 2001538 A3 20010815; CZ 302862 B6 20111221; DE 69937206 D1 20071108; DE 69937206 T2 20080619; DE 69938743 D1 20080626; DK 1264599 T3 20080204; EP 1105152 A1 20010613; EP 1247531 A2 20021009; EP 1247531 A3 20021218; EP 1247531 B1 20080514; EP 1264599 A1 20021211; EP 1264599 B1 20070926; ES 2296872 T3 20080501; HK 1051805 A1 20030822; HU 227661 B1 20111028; HU P0103117 A2 20011228; HU P0103117 A3 20040301; IL 141064 A0 20020210; IL 141064 A 20090901; JP 2002522508 A 20020723; JP 4542266 B2 20100908; NZ 509604 A 20030530; PL 203706 B1 20091130; PL 345997 A1 20020114; PT 1264599 E 20080107; TR 200100338 T2 20011221; US 2003105021 A1 20030605; US 2003185791 A1 20031002; US 7258861 B2 20070821; ZA 200100656 B 20050629
DOCDB simple family (application)
EP 9905806 W 19990810; AT 02077256 T 19990810; AT 02077274 T 19990810; AU 5620999 A 19990810; BR 9912899 A 19990810; CA 2334941 A 19990810; CN 99809655 A 19990810; CZ 2001538 A 19990810; DE 69937206 T 19990810; DE 69938743 T 19990810; DK 02077256 T 19990810; EP 02077256 A 19990810; EP 02077274 A 19990810; EP 99942835 A 19990810; ES 02077256 T 19990810; HK 03103102 A 20030430; HU P0103117 A 19990810; IL 14106401 A 20010124; IL 14106499 A 19990810; JP 2000564651 A 19990810; NZ 50960499 A 19990810; PL 34599799 A 19990810; PT 02077256 T 19990810; TR 200100338 T 19990810; US 16255302 A 20020606; US 77970301 A 20010209; ZA 200100656 A 20010123