EP 1255781 A1 20021113 - ANTIBODY BINDING SUPERFICIAL ZONE PROTEIN AND THEIR USES IN DIAGNOSIS AND SCREENING METHODS
Title (en)
ANTIBODY BINDING SUPERFICIAL ZONE PROTEIN AND THEIR USES IN DIAGNOSIS AND SCREENING METHODS
Title (de)
ANTIKÖRPER GEGEN DAS "SUPERFICIAL ZONE PROTEIN" UND IHRE VERWENDUNG IN NACHWEISVERFAHREN
Title (fr)
PROTEINES DE ZONE SUPERFICIELLE LIEES A UN ANTICORPS ET LEURS UTILISATIONS DANS LE CADRE DE PROCEDES DE FILTRAGE ET DE DIAGNOSTIC
Publication
Application
Priority
- GB 0003092 A 20000210
- US 0104372 W 20010209
- US 18137700 P 20000209
- US 20198900 P 20000503
Abstract (en)
[origin: WO0158958A1] The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BIAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
IPC 1-7
IPC 8 full level
C07K 16/18 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
C07K 16/18 (2013.01); G01N 33/6887 (2013.01); A61K 2039/53 (2013.01); C12N 2799/026 (2013.01); G01N 2500/00 (2013.01); G01N 2800/105 (2013.01); G01N 2800/52 (2013.01)
Citation (search report)
See references of WO 0158958A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0158958 A1 20010816; WO 0158958 A9 20021017; EP 1255781 A1 20021113
DOCDB simple family (application)
US 0104372 W 20010209; EP 01909099 A 20010209