EP 1255991 A2 20021113 - DEVICE AND METHOD FOR DETECTING THE COAGULATION FUNCTIONS OF GLOBAL, ESPECIALLY PRIMARY HEMOSTASIS
Title (en)
DEVICE AND METHOD FOR DETECTING THE COAGULATION FUNCTIONS OF GLOBAL, ESPECIALLY PRIMARY HEMOSTASIS
Title (de)
VORRICHTUNG UND VERFAHREN ZUR ERFASSUNG VON GERINNUNGS-FUNKTIONEN DER GLOBALEN, INSBESONDERE DER PRIMÄREN HÄMOSTASE
Title (fr)
DISPOSITIF ET PROCEDE POUR DETERMINER LES FONCTIONS DE COAGULATION DE L'HEMOSTASE GLOBALE, NOTAMMENT PRIMAIRE
Publication
Application
Priority
- DE 10003093 A 20000125
- EP 0100763 W 20010124
Abstract (en)
[origin: US2003130596A1] The invention relates to a method and to a device for examining the properties of the global, in particular the primary, hemostasis functions in whole blood or platelet-rich plasma, comprising a storage chamber (15) for the blood to be examined, a reaction device (39) having at least one flow path (5, 16) via which the blood to be examined is transported for carrying out certain reactions, a conveyor device (1) which conveys a volumetric flow for the transport of the blood through the reaction device (39), thereby generating a conveyor pressure, a pressure gauge (8, 9) which in a blood-free pressure gauge chamber (3) measures changes in the conveyor pressure which appear depending on the reactions of the blood to be examined which have taken place in the reaction device (39), a blood collection chamber (10) for collecting the blood transported through the reaction device (39), the conveyor pressure in a pressure-sealed working chamber (12) being generated by a piston-cylinder system (1), a working surface (33) of the piston (4) forming a boundary of the working chamber (12), and the working chamber (12) being formed by the blood collection chamber (10) and the blood-free pressure gauge chamber (3). According to the method of the invention, the volumetric flow is preferably adjusted, depending on the measured pressure of the volumetric flow, in such a way that the shear rate or the shear force, whose action in the reaction opening causes blood components, in particular thrombocytes, to deposit, follows a predetermined characteristic curve and in particular is held constant.
IPC 1-7
IPC 8 full level
G01N 33/86 (2006.01); G01N 33/49 (2006.01); G01N 11/08 (2006.01)
CPC (source: EP US)
G01N 33/4905 (2013.01 - EP US); G01N 11/08 (2013.01 - EP US)
Citation (search report)
See references of WO 0155715A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
US 2003130596 A1 20030710; US 7223365 B2 20070529; AT E434182 T1 20090715; AU 3922801 A 20010807; DE 10003093 A1 20010802; DE 10003093 C2 20020516; DE 50114942 D1 20090730; EP 1255991 A2 20021113; EP 1471353 A2 20041027; EP 1471353 A3 20050817; EP 1471353 B1 20090617; ES 2328690 T3 20091117; JP 2003524780 A 20030819; JP 4602626 B2 20101222; WO 0155715 A2 20010802; WO 0155715 A3 20020314
DOCDB simple family (application)
US 18223802 A 20021118; AT 04017857 T 20010124; AU 3922801 A 20010124; DE 10003093 A 20000125; DE 50114942 T 20010124; EP 0100763 W 20010124; EP 01913766 A 20010124; EP 04017857 A 20010124; ES 04017857 T 20010124; JP 2001555805 A 20010124