Global Patent Index - EP 1257567 A2

EP 1257567 A2 2002-11-20 - CATIONIC, AMPHIPATHIC BETA-SHEET PEPTIDES AND USES THEREOF

Title (en)

CATIONIC, AMPHIPATHIC BETA-SHEET PEPTIDES AND USES THEREOF

Title (de)

KATIONISCHE AMPHIPATISCHE BETA-FALTBLATT PEPTIDE UND DEREN VERWENDUNGEN

Title (fr)

PEPTIDES CATIONIQUES PRESENTANT UNE STRUCTURE SECONDAIRE AMPHIPATIQUE DE FEUILLET BETA ET LEURS UTILISATIONS

Publication

EP 1257567 A2 (EN)

Application

EP 01912747 A

Priority

  • US 0104822 W
  • US 18249500 P

Abstract (en)

[origin: WO0160162A2] This invention relates to an antimicrobial compound which is (a) a peptide having a length of 8-50 amino acids, a net charge of at least four, a hydrophobic moment as a beta sheet which is at least 0.2 higher than its hydrophobic moment as an alpha helix, and having dectectable membrane disrupting activity against at least one microbial pathogen, and substantially no membrane disrupting activity against mammalian cells, or (b) a peptoid, petidomimetic or nonpeptidic analogue of a peptide according to (a) above. And to antimicrobial use thereof.

IPC 1-7 (main, further and additional classification)

C07K 7/08; C07K 14/47; A61P 31/00

IPC 8 full level (invention and additional information)

A61K 38/00 (2006.01); A61P 15/00 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01)

CPC (invention and additional information)

C07K 7/08 (2013.01); C07K 14/001 (2013.01); C07K 14/4723 (2013.01); A61K 38/00 (2013.01); Y02A 50/473 (2018.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0160162 A2 20010823; WO 0160162 A3 20020502; WO 0160162 A9 20030821; AU 4149401 A 20010827; AU 783021 B2 20050915; CA 2399668 A1 20010823; EP 1257567 A2 20021120; JP 2003522775 A 20030729

INPADOC legal status


2007-08-15 [18R] REFUSED

- Effective date: 20070406

2003-08-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030714

2003-01-15 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: BLAZYK, JOHN F., C/O OHIO UNIVERSITY

2003-01-02 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20021104

2002-11-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR