EP 1257574 A1 20021120 - IMPROVED INTERLEUKIN 10
Title (en)
IMPROVED INTERLEUKIN 10
Title (de)
VERBESSERTES INTERLEUKIN 10
Title (fr)
INTERLEUKINE-10 AMELIOREE
Publication
Application
Priority
- DK 0100091 W 20010209
- DK PA200000221 A 20000211
- DK PA200001325 A 20000905
- US 18402400 P 20000222
- US 23009300 P 20000905
Abstract (en)
[origin: WO0158950A1] Conjugates exhibiting IL-10 activity comprising (i) a polypeptide which comprises an amino acid sequence that differs from that of human IL-10 in at least one amino acid residue selected from an introduced or removed amino acid residue comprising an attachment group for the non-polypeptide moiety of (ii), and (ii) a non-polypeptide moiety. The conjugates have increased half-life as compared to hIL-10 and may be used for treatment of, e.g., inflammatory diseases.
IPC 1-7
IPC 8 full level
A61K 47/48 (2006.01); C07K 14/54 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 47/60 (2017.07); C07K 14/5428 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 0158950A1
Citation (examination)
EP 0370205 A2 19900530 - KYOWA HAKKO KOGYO KK [JP]
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0158950 A1 20010816; AU 3153201 A 20010820; EP 1257574 A1 20021120
DOCDB simple family (application)
DK 0100091 W 20010209; AU 3153201 A 20010209; EP 01903608 A 20010209