Global Patent Index - EP 1257654 A1

EP 1257654 A1 2002-11-20 - M CELL DIRECTED VACCINES

Title (en)

M CELL DIRECTED VACCINES

Title (de)

IMPFSTOFFE MIT SPEZIFITÄT FÜR M ZELLEN

Title (fr)

VACCINS AGISSANT SUR LES CELLULES M

Publication

EP 1257654 A1 (EN)

Application

EP 01901811 A

Priority

  • US 0100426 W
  • US 17478600 P

Abstract (en)

[origin: WO0149867A1] This invention provides a vaccine that can direct gene transfer to follicle associated epithelium or M cells to induce mucosal immunity using M cell ligands for receptor-mediated endocytosis. Also provided are polynucleotides sequences encoding M cell ligand-polybasic component fusion proteins, host cells, and methods of producing such proteins recombinantly and chemically. Further, methods are described for immunizing animal and human subjects against bacterial, viral, parasitic, fungal infectious agents or cancer and methods for assaying mucosal immunity using this vaccine.

IPC 1-7 (main, further and additional classification)

C12N 15/62; C12N 5/10; C07K 14/105; C07K 14/255; C07K 14/14; C07K 19/00; C07K 16/18; C07K 16/10; C12N 15/87; C12N 15/11; G01N 33/53; A61K 39/00; A61K 48/00

IPC 8 full level (invention and additional information)

A61K 47/48 (2006.01); C07K 14/105 (2006.01); C07K 14/14 (2006.01); C07K 14/255 (2006.01); C07K 19/00 (2006.01)

CPC (invention and additional information)

C07K 19/00 (2013.01); A61K 47/646 (2017.08); C07K 14/005 (2013.01); C07K 14/255 (2013.01); C07K 2319/00 (2013.01); C12N 2720/12022 (2013.01); C12N 2770/32622 (2013.01); Y02A 50/41 (2018.01); Y02A 50/412 (2018.01); Y02A 50/466 (2018.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0149867 A1 20010712; AU 2767201 A 20010716; EP 1257654 A1 20021120

INPADOC legal status


2004-09-01 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20040226

2003-12-03 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031015

2002-11-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020730

2002-11-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-11-20 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI