Global Patent Index - EP 1257657 A2

EP 1257657 A2 2002-11-20 - AUTOREGULATORY EXPRESSION VECTOR FOR GENE THERAPY

Title (en)

AUTOREGULATORY EXPRESSION VECTOR FOR GENE THERAPY

Title (de)

SELBSTREGULIERENDER EXPRESSIONSVEKTOR FÜR DIE GENTHERAPIE

Title (fr)

VECTEUR

Publication

EP 1257657 A2 (EN)

Application

EP 01904135 A

Priority

  • GB 0100540 W
  • GB 0003198 A
  • GB 0027663 A

Abstract (en)

[origin: WO0159088A2] A autoregulatory expression vector is provided which comprises a nucleic acid sequence encoding reverse tetracycline transactivator which binds to a tet operon containing promoter in the presence of doxycycline thereby inducing expression of a protein of interest. The vector finds application in gene therapy in the treatment of chronic conditions displaying relapsing symptoms.

IPC 1-7 (main, further and additional classification)

C12N 15/867; A61K 48/00; C12N 15/63

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/7088 (2006.01); A61K 35/12 (2006.01); A61K 35/74 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); C12N 15/867 (2006.01)

CPC (invention and additional information)

C12N 15/86 (2013.01); C12N 15/635 (2013.01); A61K 48/00 (2013.01); C12N 2740/13043 (2013.01); C12N 2830/003 (2013.01)

Citation (search report)

See references of WO 0159088A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0159088 A2 20010816; WO 0159088 A3 20011227; AU 3205401 A 20010820; EP 1257657 A2 20021120; JP 2003521941 A 20030722

INPADOC legal status


2004-12-08 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20040513

2004-02-11 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040102

2002-11-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020909

2002-11-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-11-20 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI