EP 1257657 A2 20021120 - AUTOREGULATORY EXPRESSION VECTOR FOR GENE THERAPY
Title (en)
AUTOREGULATORY EXPRESSION VECTOR FOR GENE THERAPY
Title (de)
SELBSTREGULIERENDER EXPRESSIONSVEKTOR FÜR DIE GENTHERAPIE
Title (fr)
VECTEUR
Publication
Application
Priority
- GB 0100540 W 20010209
- GB 0003198 A 20000211
- GB 0027663 A 20001113
Abstract (en)
[origin: WO0159088A2] A autoregulatory expression vector is provided which comprises a nucleic acid sequence encoding reverse tetracycline transactivator which binds to a tet operon containing promoter in the presence of doxycycline thereby inducing expression of a protein of interest. The vector finds application in gene therapy in the treatment of chronic conditions displaying relapsing symptoms.
IPC 1-7
IPC 8 full level
A61K 31/7088 (2006.01); A61K 35/12 (2006.01); A61K 35/74 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01); C12N 15/867 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C12N 15/635 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2740/13043 (2013.01); C12N 2830/003 (2013.01)
Citation (search report)
See references of WO 0159088A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0159088 A2 20010816; WO 0159088 A3 20011227; AU 3205401 A 20010820; EP 1257657 A2 20021120; JP 2003521941 A 20030722
DOCDB simple family (application)
GB 0100540 W 20010209; AU 3205401 A 20010209; EP 01904135 A 20010209; JP 2001558228 A 20010209