Global Patent Index - EP 1259232 A1

EP 1259232 A1 2002-11-27 - METHOD FOR IDENTIFYING AN AGENT FOR TREATMENT OF NIDDMDIABETES BY INTERACTION WITH COMPOUND U0126

Title (en)

METHOD FOR IDENTIFYING AN AGENT FOR TREATMENT OF NIDDMDIABETES BY INTERACTION WITH COMPOUND U0126

Title (de)

VERFAHREN ZUR IDENTIFIZIERUNG EINES MITTELS ZUR BEHANDLUNG VON NIDD-DIABETES DURCH INTERAKTION MIT EINER UO126-VERBINDUNG

Title (fr)

PROCEDE D'IDENTIFICATION D'UN AGENT POUR LE TRAITEMENT DU DIABETE DNID PAR INTERACTION AVEC UN COMPOSE UO126

Publication

EP 1259232 A1 (EN)

Application

EP 01912628 A

Priority

  • SE 0100450 W
  • SE 0000718 A

Abstract (en)

[origin: WO0164209A1] The present invention relates to a method for identifying an agent useful for the treatment or prevention of a medical condition related to reduced cellular uptake of glucose, said method comprising the steps of: (i) identifying a target polypeptide interacting with the compound U0126 (1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene); (ii) contacting a candidate agent with the said target polypeptide; and (iii) determining whether said candidate agent modulates the biological activities of the said target polypeptide, such modulation being indicative for an agent useful for the treatment or prevention of a medical condition related to reduced cellular uptake of glucose.

IPC 1-7 (main, further and additional classification)

A61K 31/145; A61P 3/10

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); C12Q 1/02 (2006.01); C12Q 1/48 (2006.01); C12Q 1/54 (2006.01); G01N 33/15 (2006.01); G01N 33/566 (2006.01); G01N 33/66 (2006.01)

CPC (invention and additional information)

C12Q 1/485 (2013.01); G01N 33/66 (2013.01)

Citation (search report)

See references of WO 0164209A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0164209 A1 20010907; AU 4131601 A 20010912; CA 2399889 A1 20010907; EP 1259232 A1 20021127; JP 2003525431 A 20030826; SE 0000718 D0 20000303

INPADOC legal status


2005-01-05 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20040704

2004-04-07 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040224

2002-11-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020812

2002-11-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-11-27 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI