Global Patent Index - EP 1259238 A1

EP 1259238 A1 2002-11-27 - STABLE ACID LABILE BENZIMIDAZOLE PHARMACEUTICAL COMPOSITIONS

Title (en)

STABLE ACID LABILE BENZIMIDAZOLE PHARMACEUTICAL COMPOSITIONS

Title (de)

STABILE PHARMAZEUTISCHE ZUSAMMENSETZUNG ENTHALTEND EIN SÄUREEMPFINDLICHES BENZIMIDAZOL

Title (fr)

COMPOSITIONS PHARMACEUTIQUES STABLES AU BENZIMIDAZOLE LABILE ACIDE

Publication

EP 1259238 A1 (EN)

Application

EP 00977823 A

Priority

  • IB 0001842 W
  • US 16676199 P

Abstract (en)

[origin: WO0137834A1] The present invention relates to a novel oral pharmaceutical stable formulation containing an acid labile benzimidazole compound, which is stabilized with a vitamin E derivative. More specifically, the composition comprises the acid labile benzimidazole compound in solution and/or suspension in oil and/or oil derivatives and a vitamin E derivative as stabilizer. A particular embodiment comprising omeprazole as acid labile benzimidazole compound and vitamin E Polyethylene glycol succinate as vitamin E stabilizer derivative is disclosed.

IPC 1-7 (main, further and additional classification)

A61K 31/4439; A61K 9/48; A61K 47/22

IPC 8 full level (invention and additional information)

A61K 9/48 (2006.01); A61K 31/355 (2006.01); A61K 31/4439 (2006.01); A61K 47/22 (2006.01)

CPC (invention and additional information)

A61K 47/22 (2013.01); A61K 9/4858 (2013.01); A61K 9/4891 (2013.01); A61K 31/355 (2013.01); A61K 31/4439 (2013.01)

Combination set (CPC)

  1. A61K 31/355 + A61K 2300/00
  2. A61K 31/4439 + A61K 2300/00

Citation (search report)

See references of WO 0137834A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0137834 A1 20010531; AU 1545301 A 20010604; CA 2392353 A1 20010531; EP 1259238 A1 20021127

INPADOC legal status


2006-01-25 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20050726

2005-03-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050114

2003-05-21 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: GALEPHAR PHARMACEUTICAL RESEARCH, INC.

2003-05-21 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: DEBOECK, ARTHUR, M.

2003-05-21 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: VAN DER BIEST, FRANCIS

2003-05-21 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: BAUDIER, PHILIPPE, R.

2002-11-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020607

2002-11-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-11-27 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI