EP 1259492 A1 20021127 - SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS
Title (en)
SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS
Title (de)
SUBSTITUIERTE PIPERAZINDERIVATE ALS INHIBITOREN DES MTP
Title (fr)
DERIVES DE PIPERAZINE SUBSTITUES UTILISES COMME INHIBITEURS DE LA PROTEINE DE TRANSFERT TRIGLYCERIDE MICROSOMALE
Publication
Application
Priority
- DE 19963235 A 19991227
- EP 0012842 W 20001216
Abstract (en)
[origin: WO0147899A1] The invention relates to substituted piperazine derivatives of general formula (I), wherein Ra to Rc, Ya, Yb, X and n have the meanings given in claim no.1, and isomers and salts thereof, especially physiologically suitable salts thereof, which are valuable inhibitors of microsomal triglyceride transfer protein (MTP). The invention also relates to medicaments containing these compounds, and to the use and production of said compounds.
IPC 1-7
C07D 241/04; A61P 7/00; A61K 31/495; C07D 405/06; C07D 243/08; A61K 31/55; C07D 401/06
IPC 8 full level
A61K 31/495 (2006.01); A61K 31/551 (2006.01); A61P 3/06 (2006.01); A61P 7/00 (2006.01); A61P 35/00 (2006.01); C07D 209/18 (2006.01); C07D 213/56 (2006.01); C07D 219/02 (2006.01); C07D 233/54 (2006.01); C07D 241/04 (2006.01); C07D 295/10 (2006.01); C07D 295/18 (2006.01); C07D 295/185 (2006.01); C07D 295/192 (2006.01); C07D 295/20 (2006.01); C07D 295/205 (2006.01); C07D 295/21 (2006.01); C07D 295/215 (2006.01); C07D 295/22 (2006.01); C07D 295/26 (2006.01); C07D 311/84 (2006.01); C07D 317/60 (2006.01); C07D 241/08 (2006.01); C07D 243/08 (2006.01)
CPC (source: EP KR US)
A61P 3/06 (2018.01 - EP); A61P 7/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); C07D 209/18 (2013.01 - EP US); C07D 213/56 (2013.01 - EP US); C07D 219/02 (2013.01 - EP US); C07D 233/64 (2013.01 - EP US); C07D 241/08 (2013.01 - EP US); C07D 243/08 (2013.01 - EP US); C07D 295/185 (2013.01 - EP US); C07D 295/192 (2013.01 - EP US); C07D 295/205 (2013.01 - EP US); C07D 295/215 (2013.01 - EP US); C07D 295/26 (2013.01 - EP US); C07D 311/84 (2013.01 - EP US); C07D 317/60 (2013.01 - EP US); C07D 403/06 (2013.01 - KR); C07C 2601/02 (2017.05 - EP US); C07C 2601/08 (2017.05 - EP US); C07C 2601/14 (2017.05 - EP US); C07C 2602/10 (2017.05 - EP US); C07C 2603/18 (2017.05 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0147899 A1 20010705; AR 027112 A1 20030312; AU 2366001 A 20010709; BG 106847 A 20030228; BR 0016780 A 20020827; CA 2394644 A1 20010705; CN 1414956 A 20030430; CO 5251384 A1 20030228; CZ 20022281 A3 20021016; DE 19963235 A1 20010705; EA 200200650 A1 20021226; EE 200200364 A 20031015; EP 1259492 A1 20021127; HU P0203855 A2 20030328; HU P0203855 A3 20040728; IL 150357 A0 20021201; JP 2003519131 A 20030617; KR 20020065916 A 20020814; MX PA02006510 A 20021129; NO 20023001 D0 20020621; NO 20023001 L 20020621; PL 355394 A1 20040419; SK 9272002 A3 20021106; TR 200201669 T2 20021021; US 2003114442 A1 20030619; UY 26501 A1 20010731; YU 49902 A 20050315; ZA 200205012 B 20030116
DOCDB simple family (application)
EP 0012842 W 20001216; AR P000106940 A 20001227; AU 2366001 A 20001216; BG 10684702 A 20020620; BR 0016780 A 20001216; CA 2394644 A 20001216; CN 00817889 A 20001216; CO 00097654 A 20001226; CZ 20022281 A 20001216; DE 19963235 A 19991227; EA 200200650 A 20001216; EE P200200364 A 20001216; EP 00987409 A 20001216; HU P0203855 A 20001216; IL 15035700 A 20001216; JP 2001549371 A 20001216; KR 20027008320 A 20020626; MX PA02006510 A 20001216; NO 20023001 A 20020621; PL 35539400 A 20001216; SK 9272002 A 20001216; TR 200201669 T 20001216; US 16892602 A 20021008; UY 26501 A 20001222; YU P49902 A 20001216; ZA 200205012 A 20020621