Global Patent Index - EP 1259492 A1

EP 1259492 A1 2002-11-27 - SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS

Title (en)

SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS

Title (de)

SUBSTITUIERTE PIPERAZINDERIVATE ALS INHIBITOREN DES MTP

Title (fr)

DERIVES DE PIPERAZINE SUBSTITUES UTILISES COMME INHIBITEURS DE LA PROTEINE DE TRANSFERT TRIGLYCERIDE MICROSOMALE

Publication

EP 1259492 A1 (DE)

Application

EP 00987409 A

Priority

  • DE 19963235 A
  • EP 0012842 W

Abstract (en)

[origin: WO0147899A1] The invention relates to substituted piperazine derivatives of general formula (I), wherein Ra to Rc, Ya, Yb, X and n have the meanings given in claim no.1, and isomers and salts thereof, especially physiologically suitable salts thereof, which are valuable inhibitors of microsomal triglyceride transfer protein (MTP). The invention also relates to medicaments containing these compounds, and to the use and production of said compounds.

IPC 1-7 (main, further and additional classification)

C07D 241/04; A61K 31/495; A61K 31/55; A61P 7/00; C07D 243/08; C07D 401/06; C07D 405/06

IPC 8 full level (invention and additional information)

A61K 31/495 (2006.01); A61K 31/551 (2006.01); A61P 3/06 (2006.01); A61P 7/00 (2006.01); A61P 35/00 (2006.01); C07D 209/18 (2006.01); C07D 213/56 (2006.01); C07D 219/02 (2006.01); C07D 233/54 (2006.01); C07D 241/04 (2006.01); C07D 295/10 (2006.01); C07D 295/18 (2006.01); C07D 295/185 (2006.01); C07D 295/192 (2006.01); C07D 295/20 (2006.01); C07D 295/205 (2006.01); C07D 295/21 (2006.01); C07D 295/215 (2006.01); C07D 295/22 (2006.01); C07D 295/26 (2006.01); C07D 311/84 (2006.01); C07D 317/60 (2006.01); C07D 241/08 (2006.01); C07D 243/08 (2006.01)

CPC (invention and additional information)

C07D 233/64 (2013.01); C07D 209/18 (2013.01); C07D 213/56 (2013.01); C07D 219/02 (2013.01); C07D 241/08 (2013.01); C07D 243/08 (2013.01); C07D 295/185 (2013.01); C07D 295/192 (2013.01); C07D 295/205 (2013.01); C07D 295/215 (2013.01); C07D 295/26 (2013.01); C07D 311/84 (2013.01); C07D 317/60 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2602/10 (2017.05); C07C 2603/18 (2017.05)

Citation (search report)

See references of WO 0147899A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0147899 A1 20010705; AR 027112 A1 20030312; AU 2366001 A 20010709; BG 106847 A 20030228; BR 0016780 A 20020827; CA 2394644 A1 20010705; CN 1414956 A 20030430; CO 5251384 A1 20030228; CZ 20022281 A3 20021016; DE 19963235 A1 20010705; EA 200200650 A1 20021226; EE 200200364 A 20031015; EP 1259492 A1 20021127; HU 0203855 A2 20030328; HU 0203855 A3 20040728; IL 150357 D0 20021201; JP 2003519131 A 20030617; KR 20020065916 A 20020814; MX PA02006510 A 20021129; NO 20023001 A 20020621; NO 20023001 D0 20020621; PL 355394 A1 20040419; SK 9272002 A3 20021106; TR 200201669 T2 20021021; US 2003114442 A1 20030619; UY 26501 A1 20010731; YU 49902 A 20050315; ZA 200205012 B 20030116

INPADOC legal status


2005-01-05 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040701

2003-03-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG

2002-11-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020729

2002-11-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-11-27 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT PAYMENT 20020729;LV PAYMENT 20020729;MK;RO PAYMENT 20020729;SI PAYMENT 20020729