EP 1259591 A2 20021127 - POLYPETPTIDES AND METHODS FOR THYMIC VACCINATION
Title (en)
POLYPETPTIDES AND METHODS FOR THYMIC VACCINATION
Title (de)
POLYPEPTIDE UND METHODE ZUR THYMUS IMPFUNG
Title (fr)
POLYPEPTIDES ET METHODES DE VACCINATION THYMIQUE
Publication
Application
Priority
- US 0031502 W 20001116
- US 16737899 P 19991124
- US 16816799 P 19991130
Abstract (en)
[origin: WO0138394A2] Methods of thymic vaccination are described, in which a polypeptide of interest is administered and which allows positive or negative selection of a T cell receptor (TCR) specificity in the thymus, to retain a desired specificity (positive) or to eliminate an undesired specificity (negative) at the level of TCR repertoire development, in order to generate TCRs which are designed to recognize disease antigens or foreign antigens, such as to treat or prevent cancers, autoimmune diseases, infections, or effects of biological warfare agents.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); C07K 7/06 (2006.01); C07K 14/145 (2006.01); C07K 14/725 (2006.01); A61K 35/12 (2015.01)
CPC (source: EP)
A61K 39/00 (2013.01); A61K 39/0008 (2013.01); C07K 7/06 (2013.01); C07K 14/005 (2013.01); A61K 2035/122 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/57 (2013.01); C12N 2760/20222 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0138394 A2 20010531; WO 0138394 A3 20020502; CA 2392387 A1 20010531; EP 1259591 A2 20021127
DOCDB simple family (application)
US 0031502 W 20001116; CA 2392387 A 20001116; EP 00983712 A 20001116