EP 1259607 A2 20021127 - PROTEIN AND GENE AND THEIR USE FOR DIAGNOSIS AND TREATMENT OF SCHIZOPHRENIA
Title (en)
PROTEIN AND GENE AND THEIR USE FOR DIAGNOSIS AND TREATMENT OF SCHIZOPHRENIA
Title (de)
PROTEIN UND GEN UND DEREN VERWENDUNG ZUR DIAGNOSE UND BEHANDLUNG VON SCHIZOPHRENIE
Title (fr)
PROTEINES, GENES ET LEUR UTILISATION DANS LE DIAGNOSTIC ET LE TRAITEMENT DE LA SCHIZOPHRENIE
Publication
Application
Priority
- GB 0100792 W 20010223
- GB 0004415 A 20000224
- US 75039500 A 20001228
Abstract (en)
[origin: WO0162785A2] The present invention provides methods and compositions for screening, diagnosis and prognosis of Schizophrenia, for monitoring the effectiveness of Schizophrenia treatment, identifying patients most likely to respond to a particular therapeutic treatment and for drug development. Schizophrenia-Associated Features (SFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides Schizophrenia-Associated Protein Isoforms (SPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated SPIs, antibodies immunospecific for SPIs, and kits comprising the aforesaid.
IPC 1-7
IPC 8 full level
A61P 25/18 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 25/18 (2017.12); C07K 14/47 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01); G01N 2500/00 (2013.01); G01N 2800/302 (2013.01)
Citation (search report)
See references of WO 0162785A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0162785 A2 20010830; WO 0162785 A3 20020131; AU 3395401 A 20010903; AU 3754301 A 20010903; EP 1259607 A2 20021127; EP 1259818 A2 20021127; WO 0163293 A2 20010830; WO 0163293 A3 20020411; WO 0163293 A8 20011018
DOCDB simple family (application)
GB 0100792 W 20010223; AU 3395401 A 20010223; AU 3754301 A 20010223; EP 01905991 A 20010223; EP 01909957 A 20010223; GB 0100783 W 20010223