Global Patent Index - EP 1259633 A1

EP 1259633 A1 2002-11-27 - DEVICE AND ELECTRODE ARRANGEMENT FOR ELECTROPHYSIOLOGICAL INVESTIGATIONS

Title (en)

DEVICE AND ELECTRODE ARRANGEMENT FOR ELECTROPHYSIOLOGICAL INVESTIGATIONS

Title (de)

VORRICHTUNG UND ELEKTRODENANORDNUNG FÜR ELEKTROPHYSIOLOGISCHE UNTERSUCHUNGEN

Title (fr)

DISPOSITIF ET SYSTEME D'ELECTRODES DESTINES A DES EXAMENS ELECTROPHYSIOLOGIQUES

Publication

EP 1259633 A1 (DE)

Application

EP 01901195 A

Priority

  • DE 10010081 A
  • EP 0100728 W

Abstract (en)

[origin: DE10010081A1] Apparatus for electro-physiological examination of biological material (11) has a carrier (12) with an array of measurement electrodes (14,15), A vessel (21) has a containment zone (24) to hold the biological material (11) and any necessary culture medium (25). The vessel (21) is placed on the carrier (12) so that the electrodes (14,15) are linked electrically with the sample holding zone (24). A counter electrode (38) measures the signals between it and the measurement electrodes (14,15) or electrically stimulates the biological material. At least one counter electrode (38) is located permanently within the sample holding zone (24). The counter electrode is located at the peripheral wall (22) of the vessel (21), at the cover, or the electrode (38) is on the carrier (12) or integrated into the carrier (12). The counter electrode (38) is produced with the same technology as for the manufacture of the measurement electrodes (14,15). The ground surface of the counter electrode is at least 103> times larger than a measurement electrode surface, at 0.1 mm2> to 1.0 cm2> and preferably 10-100 mm2>. The counter electrode (38) has a structured surface on the line of the conductor path, to contact the micro-electrodes, e.g. a half-moon or wedge-shaped surface cover. The counter electrode (38) is directly adjacent to the electrode array. The counter electrode (38) is connected electrically to a connecting surface (41) on the carrier (12), outside the sample holding zone (24).

[origin: DE10010081A1] Apparatus for electro-physiological examination of biological material (11) has a carrier (12) with an array of measurement electrodes (14,15), A vessel (21) has a containment zone (24) to hold the biological material (11) and any necessary culture medium (25). The vessel (21) is placed on the carrier (12) so that the electrodes (14,15) are linked electrically with the sample holding zone (24). A counter electrode (38) measures the signals between it and the measurement electrodes (14,15) or electrically stimulates the biological material. At least one counter electrode (38) is located permanently within the sample holding zone (24). The counter electrode is located at the peripheral wall (22) of the vessel (21), at the cover, or the electrode (38) is on the carrier (12) or integrated into the carrier (12). The counter electrode (38) is produced with the same technology as for the manufacture of the measurement electrodes (14,15). The ground surface of the counter electrode is at least 10<3> times larger than a measurement electrode surface, at 0.1 mm<2> to 1.0 cm<2> and preferably 10-100 mm<2>. The counter electrode (38) has a structured surface on the line of the conductor path, to contact the micro-electrodes, e.g. a half-moon or wedge-shaped surface cover. The counter electrode (38) is directly adjacent to the electrode array. The counter electrode (38) is connected electrically to a connecting surface (41) on the carrier (12), outside the sample holding zone (24).

IPC 1-7 (main, further and additional classification)

C12Q 1/00; A61B 5/00; G01N 33/487

IPC 8 full level (invention and additional information)

A61B 5/00 (2006.01); C12M 1/34 (2006.01); G01N 33/487 (2006.01)

CPC (invention and additional information)

A61B 5/145 (2013.01); G01N 33/4836 (2013.01)

Citation (search report)

See references of WO 0164940A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

DE 10010081 A1 20010913; EP 1259633 A1 20021127; US 2003009112 A1 20030109; WO 0164940 A1 20010907

INPADOC legal status


2007-01-24 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060801

2003-01-02 [RIN1] INVENTOR (CORRECTION)

- Inventor name: HAEMMERLE, HUGO

2003-01-02 [RIN1] INVENTOR (CORRECTION)

- Inventor name: NISCH, WILFRIED

2003-01-02 [RIN1] INVENTOR (CORRECTION)

- Inventor name: LEIBROCK, CORNELIA

2003-01-02 [RIN1] INVENTOR (CORRECTION)

- Inventor name: MARTIN, DIETER

2002-11-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020920

2002-11-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR