EP 1259812 A2 20021127 - BREAST, GASTRIC AND PROSTATE CANCER ASSOCIATED ANTIGENS AND USES THEREFOR
Title (en)
BREAST, GASTRIC AND PROSTATE CANCER ASSOCIATED ANTIGENS AND USES THEREFOR
Title (de)
MIT BRUST-, MAGEN- UND PROSTATAKREBS IN VERBINDUNG STEHENDE ANTIGENE UND DEREN VERWENDUNG
Title (fr)
ANTIGENES ASSOCIES AU CANCER DU SEIN, DE LA PROSTATE ET DE L'ESTOMAC ET LEUR UTILISATION
Publication
Application
Priority
- US 0014749 W 20000526
- US 13652699 P 19990528
- US 15345499 P 19990910
Abstract (en)
[origin: WO0073801A2] Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in breast, gastric and prostate cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with cancer. The invention provides, <i>inter alia</i>, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided. The molecules provided by the invention can be used in the diagnosis, monitoring, research, or treatment of conditions characterized by the expression of one or more cancer associated antigens.
IPC 1-7
G01N 33/574; C12Q 1/68; A61K 39/00; A61K 39/395; A61K 35/14; A61K 48/00; C12N 15/63; C12N 5/10; C07K 14/47; C07K 7/04; C07K 16/18
IPC 8 full level
G01N 33/50 (2006.01); A61K 31/7088 (2006.01); A61K 35/12 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP US)
A61K 39/001194 (2018.08 - EP US); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/4748 (2013.01 - EP); G01N 33/57484 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 2039/5152 (2013.01 - EP); A61K 2039/5156 (2013.01 - EP); A61K 2039/53 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0073801 A2 20001207; WO 0073801 A3 20020912; AU 5047800 A 20001218; EP 1259812 A2 20021127; JP 2003518364 A 20030610
DOCDB simple family (application)
US 0014749 W 20000526; AU 5047800 A 20000526; EP 00932804 A 20000526; JP 2001500870 A 20000526