Global Patent Index - EP 1264183 A2

EP 1264183 A2 20021211 - DIAGNOSIS AND TREATMENT OF VASCULAR DEMENTIA

Title (en)

DIAGNOSIS AND TREATMENT OF VASCULAR DEMENTIA

Title (de)

DIAGNOSE UND BEHANDLUNG VASKULARER DEMENZ

Title (fr)

LE DIAGNOSTIC ET LE TRAITEMENT DE LA DEMENCE VASCULAIRE

Publication

EP 1264183 A2 20021211 (EN)

Application

EP 01911898 A 20010314

Priority

  • GB 0101106 W 20010314
  • GB 0006285 A 20000315
  • GB 0028734 A 20001124
  • US 72439100 A 20001128

Abstract (en)

[origin: WO0169261A2] The present invention provides methods and compositions for screening, diagnosis and prognosis of Vascular Dementia, for monitoring the effectiveness of Vascular Dementia treatment, identifying patients most likely to respond to a particular therapeutic treatment and for drug development. Vascular Dementia-Associated Features (VFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides Vascular Dementia-Associated Protein Isoforms (VPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated VPIs, antibodies immunospecific for VPIs, and kits comprising the aforesaid.

IPC 1-7

G01N 33/68; C07K 14/47; A61P 9/10; A61P 25/28; A61K 38/17

IPC 8 full level

A61P 9/10 (2006.01); A61P 25/28 (2006.01); C07K 14/47 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61P 9/10 (2017.12); A61P 25/28 (2017.12); C07K 14/47 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); G01N 2500/00 (2013.01); G01N 2550/00 (2013.01); G01N 2800/2814 (2013.01)

Citation (search report)

See references of WO 0169261A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0169261 A2 20010920; WO 0169261 A3 20020516; AU 4082001 A 20010924; EP 1264183 A2 20021211

DOCDB simple family (application)

GB 0101106 W 20010314; AU 4082001 A 20010314; EP 01911898 A 20010314