EP 1272214 A1 20030108 - VACCINE AGAINST CANCEROUS DISEASES WHICH IS BASED ON MIMOTOPES OF ANTIGENS EXPRESSED ON TUMOR CELLS
Title (en)
VACCINE AGAINST CANCEROUS DISEASES WHICH IS BASED ON MIMOTOPES OF ANTIGENS EXPRESSED ON TUMOR CELLS
Title (de)
VAKZINE GEGEN KREBSERKRANKUNGEN DIE SICH STÜTZT AUF MIMOTOPE VON AUF TUMORZELLEN EXPRIMIERTE ANTIGENEN
Title (fr)
VACCIN CONTRE DES MALADIES CANCEREUSES, A BASE DE MIMOTOPES D'ANTIGENES EXPRIMES SUR DES CELLULES TUMORALES
Publication
Application
Priority
- DE 10018403 A 20000413
- DE 10041342 A 20000823
- EP 0104251 W 20010412
Abstract (en)
[origin: WO0178766A1] The invention relates to a method for producing a vaccine against cancerous diseases and to the vaccine itself. The invention provides that, firstly while using one or more antibodies, which are specifically active against one or more antigens specially expressed by the tumor cells, one or more mimotopes of these antigens is/are selected from a phage-peptide library. In order to obtain the vaccine, these mimotopes, in the form of monomers, dimers, trimers or oligomers, are conjugated once or repeatedly with a macromolecular support. The inventively produced vaccines, when administered, lead to a humoral immune response and thus lead to the emergence of an active immunity following the vaccination.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); C07K 16/32 (2006.01)
CPC (source: EP US)
A61K 39/0011 (2013.01 - EP US); A61P 35/00 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C07K 16/32 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0178766 A1 20011025; AU 2001252262 B2 20060202; AU 5226201 A 20011030; CA 2405290 A1 20011025; CA 2405290 C 20110621; EP 1272214 A1 20030108; IL 152054 A0 20030529; US 2005100551 A1 20050512; US 7166694 B2 20070123
DOCDB simple family (application)
EP 0104251 W 20010412; AU 2001252262 A 20010412; AU 5226201 A 20010412; CA 2405290 A 20010412; EP 01925550 A 20010412; IL 15205401 A 20010412; US 25760303 A 20030311