EP 1272646 A2 20030108 - REGULATION OF HUMAN SERINE RACEMASE ENZYME
Title (en)
REGULATION OF HUMAN SERINE RACEMASE ENZYME
Title (de)
REGULATION DER HUMANEN SERIN-RACEMASE ENZYME
Title (fr)
REGULATION DE SERINE RACEMASE HUMAINE
Publication
Application
Priority
- EP 0103668 W 20010330
- US 19374800 P 20000331
- US 19424900 P 20000403
Abstract (en)
[origin: WO0173077A2] Human serine racemase enzyme can be regulated to increase or decrease D-serine formation, which thereby results in a corresponding increase or decrease in NMDA receptor activation. A decrease in D-serine formation may aid in the prevention of neuron damage following an ischemic event, such as stroke. Regulation of D-serine formation may also aid in the treatment of other neurodegenerative conditions caused by the over- or under-activation of the glutamate NMDA receptor.
IPC 1-7
C12N 15/61; C12N 15/70; C12N 9/90; A61K 31/713; C12Q 1/68; G01N 33/68
IPC 8 full level
A61K 31/713 (2006.01); C12N 9/90 (2006.01); C12N 15/61 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 31/713 (2013.01); C12N 9/90 (2013.01); C12Y 501/01018 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 0173077A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0173077 A2 20011004; WO 0173077 A3 20021003; AU 5040801 A 20011008; EP 1272646 A2 20030108
DOCDB simple family (application)
EP 0103668 W 20010330; AU 5040801 A 20010330; EP 01923705 A 20010330