EP 1274422 A1 20030115 - METHOD FOR TREATING CELLS RESISTANT TO ANTINEOPLASTIC AGENTS
Title (en)
METHOD FOR TREATING CELLS RESISTANT TO ANTINEOPLASTIC AGENTS
Title (de)
VERFAHREN ZUR BEHANDLUNG VON ANTINEOPLASTIKA-RESISTENTEN ZELLEN
Title (fr)
PROCEDE DE TRAITEMENT POUR CELLULES RESISTANT AUX AGENTS ANTINEOPLASIQUES
Publication
Application
Priority
US 0008904 W 20000404
Abstract (en)
[origin: WO0174355A1] The present invention relates to methods for treating multidrug resistant cells, preferably multidrug resistant cancer cells with discodermolide. Discodermolide is found to be effective in limiting the growth of otherwise growth unregulated cells having tubulin mutations and in promoting phosphorylation of the oncogene RAF-1.
IPC 1-7
IPC 8 full level
C07D 309/30 (2006.01); A61K 31/366 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/366 (2013.01); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 0174355A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0174355 A1 20011011; AU 4194800 A 20011015; CA 2401104 A1 20011011; EP 1274422 A1 20030115; JP 2004505890 A 20040226
DOCDB simple family (application)
US 0008904 W 20000404; AU 4194800 A 20000404; CA 2401104 A 20000404; EP 00921658 A 20000404; JP 2001572099 A 20000404