EP 1274691 A1 20030115 - 2-GUANIDINO-4-ARYLCHINAZOLINES AS NHE-3 INHIBITORS
Title (en)
2-GUANIDINO-4-ARYLCHINAZOLINES AS NHE-3 INHIBITORS
Title (de)
2-GUANIDINO-4-ARYL-CHINAZOLINE ALS NHE-3-INHIBITOREN
Title (fr)
2-GUANIDINO-4-ARYLQUINAZOLINES UTILISEES COMME INHIBITEURS DE NHE-3
Publication
Application
Priority
- DE 10019062 A 20000418
- EP 0103281 W 20010322
Abstract (en)
[origin: WO0179186A1] The invention relates to compounds of formula (I), where Ar = unsubstituted, or monosubstituted by R<3>, phenyl, or naphthyl; R<1>, R<2> = independently, A, OA, Hal or CF3; R<3> = A, OA, Hal, or CF3; A = 1-6C alkyl and Hal = F, Cl, Br or I and the salts and solvates thereof as NHE3 inhibitors.
IPC 1-7
IPC 8 full level
A61K 31/517 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 7/00 (2006.01); A61P 7/02 (2006.01); A61P 7/10 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 13/08 (2006.01); A61P 13/12 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 239/84 (2006.01)
CPC (source: EP KR US)
A61P 3/06 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 7/00 (2018.01 - EP); A61P 7/02 (2018.01 - EP); A61P 7/10 (2018.01 - EP); A61P 9/08 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 9/12 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 13/08 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 21/00 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 239/84 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0179186 A1 20011025; AR 028914 A1 20030528; AU 9337301 A 20011030; BR 0109867 A 20030603; CA 2406161 A1 20021016; CN 1422260 A 20030604; DE 10019062 A1 20011025; EP 1274691 A1 20030115; HU P0300909 A2 20031028; HU P0300909 A3 20040128; JP 2004501082 A 20040115; KR 20030011789 A 20030211; MX PA02010264 A 20030425; NO 20024997 D0 20021017; NO 20024997 L 20021017; PL 356559 A1 20040628; RU 2002130246 A 20040327; SK 13472002 A3 20030204; US 2004224965 A1 20041111; ZA 200209274 B 20040216
DOCDB simple family (application)
EP 0103281 W 20010322; AR P010101808 A 20010418; AU 9337301 A 20010322; BR 0109867 A 20010322; CA 2406161 A 20010322; CN 01807951 A 20010322; DE 10019062 A 20000418; EP 01969043 A 20010322; HU P0300909 A 20010322; JP 2001576787 A 20010322; KR 20027011796 A 20020909; MX PA02010264 A 20010322; NO 20024997 A 20021017; PL 35655901 A 20010322; RU 2002130246 A 20010322; SK 13472002 A 20010322; US 25763602 A 20021016; ZA 200209274 A 20021114