EP 1276710 A1 20030122 - NEW COMPOUNDS, THEIR PREPARATION AND USE
Title (en)
NEW COMPOUNDS, THEIR PREPARATION AND USE
Title (de)
NEUE VERBINDUNGEN, IHRE HERSTELLUNG UND VERWENDUNG
Title (fr)
NOUVEAUX COMPOSES, LEUR PREPARATION ET LEUR UTILISATION
Publication
Application
Priority
- DK 0100236 W 20010406
- DK PA200000650 A 20000417
Abstract (en)
[origin: WO0179150A1] The present invention relates to compounds of the general formula (I). The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR), wherein R<1>, R<2>, R<3> and R<4> independently of each other are hydrogen, C1-12-alkyl, C2-12-alkenyl, C2-12-alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl or C1-6-alkoxyC1-6-alkyl, optionally substituted with one or more halogen, hydroxy or amino; and X1, X2, X3 and X4 independently of each other is carbon, oxygen, sulphur or nitrogen; and Y is C1-12-alkyl, C2-12-alkenyl, C2-12-alkynyl, aryl, aralkyl, alkylaralkyl, heteroaryl, heteroaralkyl, or alkylheteroaralkyl, optionally substituted with one or more halogen, hydroxy or amino; and Ar<1> and Ar<2> independently of each other are aryl or heteroaryl optionally substituted with one or more halogen, hydroxy, amino, aminoalkyl, carboxyalkyl, C1-6-alkyl or C1-6-alkoxy; or a salt thereof with a pharmaceutically acceptable acid or base, or any optical isomer or mixture of optical isomers, including a racemic mixture, or any tautomeric forms.
IPC 1-7
IPC 8 full level
A61P 3/04 (2006.01); A61K 31/216 (2006.01); A61P 3/10 (2006.01); C07C 69/732 (2006.01); C07C 69/734 (2006.01)
CPC (source: EP)
A61P 3/04 (2017.12); A61P 3/10 (2017.12); C07C 69/732 (2013.01); C07C 69/734 (2013.01)
Citation (search report)
See references of WO 0179150A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0179150 A1 20011025; AU 4827901 A 20011030; EP 1276710 A1 20030122; JP 2004501076 A 20040115
DOCDB simple family (application)
DK 0100236 W 20010406; AU 4827901 A 20010406; EP 01921239 A 20010406; JP 2001576752 A 20010406