EP 1280824 A2 20030205 - HUMAN ION CHANNELS
Title (en)
HUMAN ION CHANNELS
Title (de)
MENSCHLICHE IONENKANNÄLE
Title (fr)
CANAUX IONIQUES HUMAINS
Publication
Application
Priority
- US 0114965 W 20010510
- US 20330500 P 20000510
- US 20652600 P 20000523
- US 20709200 P 20000525
- US 20703300 P 20000525
- US 20709300 P 20000525
- US 21689300 P 20000707
- US 22324500 P 20000804
- US 23787300 P 20001004
Abstract (en)
[origin: WO0185788A2] The present invention provides novel ion channel polypeptides and polynucleotides that identify and encode them. In addition, the invention provides expression vectors, host cells and methods for their production. The inventin also provides methods for the identification of ion channel agonists/antagonists, useful for the treatment of human diseases and conditions.
IPC 1-7
C07K 14/705; C12N 15/12; C12N 5/10; C07K 16/28; G01N 33/53; C12Q 1/68; C07K 19/00; C12N 15/62
IPC 8 full level
C07K 14/705 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/705 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12N 2799/026 (2013.01)
Citation (search report)
See references of WO 0185788A2
Citation (examination)
- BANG H. ET AL: "TREK-2, a New Member of the Mechanosensitive Tandem-pore K+ Channel Family", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 23, 9 June 2000 (2000-06-09), pages 17412 - 17419
- LESAGE F. ET AL: "Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids and Gs, Gi, and Gq protein-coupled receptors", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 37, 2000, pages 28398 - 28405
- GU W. ET AL: "Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2", JOURNAL OF PHYSIOLOGY, vol. 539, no. 3, 2002, pages 657 - 668
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0185788 A2 20011115; WO 0185788 A3 20020718; AU 5757001 A 20011120; EP 1280824 A2 20030205
DOCDB simple family (application)
US 0114965 W 20010510; AU 5757001 A 20010510; EP 01931099 A 20010510