EP 1287121 A2 20030305 - EXTRACELLULAR DOMAIN OF RYK PROTEIN FOR REGULATING ANGIOGENESIS
Title (en)
EXTRACELLULAR DOMAIN OF RYK PROTEIN FOR REGULATING ANGIOGENESIS
Title (de)
EXTRAZELLULÄRE DOMÄNE DER RYK PROTEINE FÜR DIE REGULIERUNG DER ANGIOGENESE
Title (fr)
PROCEDE DE REGULATION DE L'ANGIOGENESE AU MOYEN DE LA PROTEINE RYK
Publication
Application
Priority
- US 0115043 W 20010509
- US 56878300 A 20000510
Abstract (en)
[origin: WO0185789A2] Ryk protein was found to have a novel activity in regulating angiogenesis. New variant Ryk proteins were constructed that were useful in modulating the capillary forming activity of endothelial cells. Variant Ryk proteins, may be employed as therapeutics in diseases such as cancer, wound healing, diabetic retinopathies, macular degeneration, and cardiovascular diseases, and other diseases or clinical conditions where angiogenesis is relevant to the causation or treatment of the disease.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/46 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 17/02 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); C07K 16/28 (2006.01); C12N 9/12 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 17/02 (2017.12); A61P 27/02 (2017.12); A61P 35/00 (2017.12); A61P 35/04 (2017.12); C07K 14/71 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 0185789A2
Designated contracting state (EPC)
DE ES FR GB IT
DOCDB simple family (publication)
WO 0185789 A2 20011115; WO 0185789 A3 20020516; AR 028424 A1 20030507; AU 6134301 A 20011120; CA 2408349 A1 20011115; CO 5300464 A1 20030731; DO P2001000164 A 20020515; EC SP014068 A 20020225; EP 1287121 A2 20030305; GT 200100079 A 20011231; JP 2004527206 A 20040909; PE 20011218 A1 20020201; SV 2002000442 A 20020703; UY 26696 A1 20011228
DOCDB simple family (application)
US 0115043 W 20010509; AR P010102149 A 20010507; AU 6134301 A 20010509; CA 2408349 A 20010509; CO 01036462 A 20010509; DO 2001000164 A 20010510; EC SP014068 A 20010509; EP 01935233 A 20010509; GT 200100079 A 20010507; JP 2001582388 A 20010509; PE 2001000417 A 20010510; SV 2001000442 A 20010509; UY 26696 A 20010508