EP 1289646 A2 20030312 - METHOD AND DEVICE FOR THE SYNTHESIS AND THE ANALYSIS OF SUPPORT-BOUND ARRAYS OF OLIGOMERS, ESPECIALLY OF PRIMER PAIRS FOR PCR, AS WELL AS OLIGOMER-CARRYING SUPPORTS
Title (en)
METHOD AND DEVICE FOR THE SYNTHESIS AND THE ANALYSIS OF SUPPORT-BOUND ARRAYS OF OLIGOMERS, ESPECIALLY OF PRIMER PAIRS FOR PCR, AS WELL AS OLIGOMER-CARRYING SUPPORTS
Title (de)
VERFAHREN UND VORRICHTUNG ZUR SYNTHESE UND ANALYSE VON TRÄGERGEBUNDENEN ARRAYS VON OLIGOMEREN, INSBESONDERE VON PRIMERPAAREN FÜR DIE PCR, SOWIE TRÄGER MIT OLIGOMEREN
Title (fr)
PROCEDE ET DISPOSITIF POUR EFFECTUER LA SYNTHESE ET L'ANALYSE D'ENSEMBLES D'OLIGOMERES, LIES A UN SUPPORT, NOTAMMENT DE PAIRES D'AMORCES POUR LA PCR, AINSI QUE SUPPORTS COMPORTANT CES OLIGOMERES
Publication
Application
Priority
- DE 0100435 W 20010202
- DE 10004659 A 20000203
- DE 10030588 A 20000621
Abstract (en)
[origin: WO0156691A2] The aim of the invention is to synthesize a support-bound array of oligomers with free ends A, said oligomers having a temporary protecting group on the 5'-OH end of the oligomers and permanent protecting groups on the reactive side-groups. To this end, the temporary protecting group is removed from the end B after the combinatorial synthesis of the oligomers onto the support. The free ends B are cross-linked before the permanent protecting groups are removed and the covalent bonds of the synthesized oligomers on the support can be removed via the end A so that free ends A are formed and so that a part of the synthesized oligomers covalently binds to the support even when the free ends A have been removed from the support.
IPC 1-7
IPC 8 full level
B01J 19/00 (2006.01); C07B 61/00 (2006.01); C07H 21/00 (2006.01); C12Q 1/68 (2006.01); C40B 40/06 (2006.01)
CPC (source: EP US)
B01J 19/0046 (2013.01 - EP US); C07H 21/00 (2013.01 - EP US); C12Q 1/6837 (2013.01 - EP US); B01J 2219/00529 (2013.01 - EP US); B01J 2219/00596 (2013.01 - EP US); B01J 2219/00605 (2013.01 - EP US); B01J 2219/00608 (2013.01 - EP US); B01J 2219/00626 (2013.01 - EP US); B01J 2219/00659 (2013.01 - EP US); B01J 2219/00702 (2013.01 - EP US); B01J 2219/00722 (2013.01 - EP US); B01J 2219/00729 (2013.01 - EP US); C07B 2200/11 (2013.01 - EP US); C40B 40/06 (2013.01 - EP US); Y02P 20/55 (2015.11 - EP US)
C-Set (source: EP US)
Citation (search report)
See references of WO 0156691A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0156691 A2 20010809; WO 0156691 A3 20021227; EP 1289646 A2 20030312; US 2004048252 A1 20040311
DOCDB simple family (application)
DE 0100435 W 20010202; EP 01911417 A 20010202; US 20308203 A 20030417