EP 1290206 A2 20030312 - RECOMBINANT AAV VECTORS FOR GENE THERAPY OF OBESITY
Title (en)
RECOMBINANT AAV VECTORS FOR GENE THERAPY OF OBESITY
Title (de)
REKOMBINANTE AAV-VEKTOREN FÜR DIE GENTHERAPIE VON FETTLEIBIGKEIT
Title (fr)
COMPOSITIONS A BASE DE VECTEUR VIRAL ASSOCIE A L'ADENOVIRUS ET LEURS UTILISATIONS THERAPEUTIQUES
Publication
Application
Priority
- US 0140901 W 20010608
- US 59081000 A 20000609
Abstract (en)
[origin: WO0194605A2] Disclosed are methods for the use of cytokine or cytokine receptor-encoding polynucleotides in the creation of transformed host cells and transgenic animals is disclosed. In particular, the use of recombinant adeno-associated viral (rAAV) vector compositions comprising polynucleotide sequences that express one or more mammalian cytokines or cytokine receptor polypeptides is described. Also disclosed are methods for the treatment and amelioration of symptoms of a variety of conditions and disorders in an animal, including blindness, retinitis pigmentosa, age-related macular degeneration, obesity, anorexia, and related eating disorders, as well as neurological and musculoskeletal disorders, including for example, amyotrophic lateral sclerosis.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); A61P 3/04 (2006.01); C07K 14/475 (2006.01); C07K 14/52 (2006.01); C07K 14/575 (2006.01); C07K 14/715 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); A61P 3/04 (2017.12); C07K 14/475 (2013.01); C07K 14/52 (2013.01); C07K 14/5759 (2013.01); C07K 14/715 (2013.01); C12N 2799/025 (2013.01)
Citation (search report)
See references of WO 0194605A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0194605 A2 20011213; WO 0194605 A3 20021205; AU 6705801 A 20011217; CA 2410512 A1 20011213; EP 1290206 A2 20030312
DOCDB simple family (application)
US 0140901 W 20010608; AU 6705801 A 20010608; CA 2410512 A 20010608; EP 01944672 A 20010608