EP 1290390 A1 20030312 - INDUSTRIAL SCALE BARRIER TECHNOLOGY FOR PRESERVATION OF SENSITIVE BIOLOGICAL MATERIALS
Title (en)
INDUSTRIAL SCALE BARRIER TECHNOLOGY FOR PRESERVATION OF SENSITIVE BIOLOGICAL MATERIALS
Title (de)
BARRIERETECHNOLOGIE IN INDUSTRIELLEM UMFANG FÜR KONSERVIERUNG VON EMPFINDLICHEN BIOLOGISCHEN MATERIALIEN
Title (fr)
TECHNOLOGIE D'ISOLATION A ECHELLE INDUSTRIELLE DESTINEE A LA PRESERVATION DE MATIERES BIOLOGIQUES SENSIBLES
Publication
Application
Priority
- US 0019667 W 20000719
- US 58938100 A 20000607
Abstract (en)
[origin: WO0194867A1] The present invention relates to an industrial scale barrier process for preserving a biologically active material and subsequent storage at temperatures above 0 DEG C. The process comprises loading an industrial scale volume of a solution or suspension containing the biologically active material into a process vessel adapted to fit within a process chamber. The solution or suspension is subjected to drying conditions, which comprise a temperature and a vacuum pressure, wherein the drying conditions are sufficient to cause the solution or suspension to boil without freezing. The drying conditions are monitored using a temperature sensor and a pressure sensor and are adjusted as required to maintain boiling without freezing by applying heat to the solution or suspension until a mechanically stable foam is formed. Optionally, subsequent crushing of the preserved biological material is used to form dry powders.
IPC 1-7
IPC 8 full level
F26B 5/04 (2006.01)
CPC (source: EP)
F26B 5/04 (2013.01)
Citation (search report)
See references of WO 0194867A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0194867 A1 20011213; AU 6491200 A 20011217; EP 1290390 A1 20030312
DOCDB simple family (application)
US 0019667 W 20000719; AU 6491200 A 20000719; EP 00952163 A 20000719