EP 1292574 A1 20030319 - 3-AZABICYCLO¬3.1.0 HEXANE DERIVATIVES HAVING OPIOID RECEPTOR AFFINITY
Title (en)
3-AZABICYCLO¬3.1.0 HEXANE DERIVATIVES HAVING OPIOID RECEPTOR AFFINITY
Title (de)
3-AZABICYCLO¬3.1.0 HEXAN DERIVATE MIT OPIOID-RECEPTOR-AFFINITÄT
Title (fr)
DERIVES 3-AZABICYCLO 3.1.0 HEXANE AYANT UNE AFFINITE POUR LE RECEPTEUR OPIOIDE
Publication
Application
Priority
- GB 0015562 A 20000623
- IB 0101035 W 20010607
Abstract (en)
[origin: WO0198267A1] Compounds of formula (I), where the substituents are as defined herein, and the pharmaceutically or veterinarily acceptable derivatives or prodrugs thereof, are pharmaceutically and veterinarily useful, in particular they bind to opiate receptors (e.g. mu, kappa and delta opioid receptors). They are likely to be useful in the treatment of diseases or conditions modulated by opiate receptors, for example irritable bowel syndrome; constipation; nausea; vomiting; pruritic dermatoses, such as allergic dermatitis and atopy; eating disorders; opiate overdoses; depression; smoking and alcohol addiction; sexual dysfunction; shock; stroke; spinal damage; and head trauma.
IPC 1-7
C07D 209/52; C07D 401/12; C07D 413/12; C07D 403/12; A61K 31/403; A61P 1/00
IPC 8 full level
A61K 31/403 (2006.01); A61K 31/4155 (2006.01); A61K 31/422 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01); A61P 1/00 (2006.01); A61P 1/08 (2006.01); A61P 1/14 (2006.01); A61P 9/00 (2006.01); A61P 15/10 (2006.01); A61P 17/04 (2006.01); A61P 25/08 (2006.01); A61P 25/24 (2006.01); A61P 25/32 (2006.01); A61P 25/34 (2006.01); A61P 25/36 (2006.01); C07D 209/52 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP KR)
A61P 1/00 (2018.01 - EP); A61P 1/08 (2018.01 - EP); A61P 1/14 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 15/00 (2018.01 - EP); A61P 15/10 (2018.01 - EP); A61P 17/00 (2018.01 - EP); A61P 17/04 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/08 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/30 (2018.01 - EP); A61P 25/32 (2018.01 - EP); A61P 25/34 (2018.01 - EP); A61P 25/36 (2018.01 - EP); C07D 209/52 (2013.01 - EP KR); C07D 401/12 (2013.01 - EP); C07D 403/12 (2013.01 - EP); C07D 413/12 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 0198267 A1 20011227; WO 0198267 A8 20030227; AP 2002002698 A0 20021231; AR 028969 A1 20030528; AU 6259101 A 20020102; AU 781837 B2 20050616; BG 107329 A 20030731; BR 0111867 A 20030701; CA 2412188 A1 20011227; CN 1639121 A 20050713; CZ 20023967 A3 20040218; DO P2001000187 A 20020330; DZ 3368 A1 20011227; EA 005117 B1 20041028; EA 200201269 A1 20030626; EP 1292574 A1 20030319; GB 0015562 D0 20000816; HR P20020998 A2 20040229; HU P0301228 A2 20030828; HU P0301228 A3 20050829; IL 153427 A0 20030706; IS 6637 A 20021128; JP 2004512263 A 20040422; KR 20040002386 A 20040107; MA 26915 A1 20041220; MX PA02012878 A 20030514; NO 20026168 D0 20021220; NO 20026168 L 20030218; NZ 523141 A 20050624; OA 12293 A 20040318; PA 8519401 A1 20021230; PE 20020253 A1 20020408; PL 365956 A1 20050124; SK 17172002 A3 20040908; TN SN01094 A1 20051110; UA 73176 C2 20050615; UY 26787 A1 20020131; YU 91802 A 20060525; ZA 200210278 B 20031219
DOCDB simple family (application)
IB 0101035 W 20010607; AP 2002002698 A 20010607; AR P010102957 A 20010621; AU 6259101 A 20010607; BG 10732902 A 20021128; BR 0111867 A 20010607; CA 2412188 A 20010607; CN 01811608 A 20010607; CZ 20023967 A 20010607; DO 2001000187 A 20010606; DZ 013368 A 20010607; EA 200201269 A 20010607; EP 01936728 A 20010607; GB 0015562 A 20000623; HR P20020998 A 20021212; HU P0301228 A 20010607; IL 15342701 A 20010607; IS 6637 A 20021128; JP 2002504223 A 20010607; KR 20027017503 A 20021221; MA 26955 A 20021216; MX PA02012878 A 20010607; NO 20026168 A 20021220; NZ 52314101 A 20010607; OA 1200200386 A 20010607; PA 8519401 A 20010612; PE 2001000604 A 20010621; PL 36595601 A 20010607; SK 17172002 A 20010607; TN SN01094 A 20010622; UA 20021210406 A 20010607; UY 26787 A 20010621; YU P91802 A 20010607; ZA 200210278 A 20021219