EP 1292709 A4 20040922 - CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS
Title (en)
CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS
Title (de)
KONJUGAT-ADDITIONSREAKTIONEN ZUR KONTROLLIERTEN ABGABE VON PHARMAZEUTISCH WIRKSAMEN SUBSTANZEN
Title (fr)
REACTIONS D'ADDITION DE CONJUGUES POUR L'ADMINISTRATION REGULEE DE COMPOSES ACTIFS SUR LE PLAN PHARMACEUTIQUE
Publication
Application
Priority
- US 0118101 W 20010604
- US 58693700 A 20000602
Abstract (en)
[origin: WO0192584A1] The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.
IPC 1-7
A61K 47/48; A61K 31/337; A61K 31/4745; A61K 31/565; A61K 31/69; A61K 31/7072; A61K 31/7042; A61K 31/724; A61K 31/727; A61K 38/18; C07H 21/04
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/337 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); A61K 31/565 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2006.01); A61K 47/36 (2006.01); A61K 47/40 (2006.01); A61K 47/48 (2006.01); A61L 27/54 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/48 (2006.01); C07K 19/00 (2006.01)
CPC (source: EP)
A61K 47/54 (2017.07); A61K 47/549 (2017.07); A61K 47/58 (2017.07); A61K 47/60 (2017.07); A61K 47/6903 (2017.07); A61K 47/6925 (2017.07); A61L 27/54 (2013.01); A61P 31/00 (2017.12); A61P 35/00 (2017.12); A61K 47/34 (2013.01); A61L 2300/252 (2013.01); A61L 2300/258 (2013.01); A61L 2300/602 (2013.01)
Citation (search report)
- [PX] WO 0044808 A1 20000803 - HUBBELL JEFFREY A [CH], et al
- [PX] WO 0102017 A2 20010111 - HOFFMANN LA ROCHE [CH]
- [X] WO 9832466 A1 19980730 - POLYMASC PHARMACEUTICALS PLC [GB], et al
- [X] US 5702717 A 19971230 - CHA YOUNSIK [US], et al
- [X] GREENWALD R B ET AL: "CAMPTOTHECIN-20-PEG ESTER TRANSPORT FORMS: THE EFFECT OF SPACER GROUPS ON ANTITUMOR ACTIVITY", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, vol. 6, 1998, pages 551 - 562, XP000985272, ISSN: 0968-0896
- [X] PENDRI ANNAPURNA ET AL: "Antitumor activity of paclitaxel-2'-glycinate conjugated to poly(ethylene glycol): A water-soluble prodrug", ANTI-CANCER DRUG DESIGN, vol. 13, no. 5, July 1998 (1998-07-01), pages 387 - 395, XP009034723, ISSN: 0266-9536
- [X] KOPECEK, REJMANOVA, DUNCAN, LLOYD: "Controlled Release of Drug Model from N-(2-Hydroxypropyl)-methacrylamide Copolymers", ANN.N.Y.ACAD.SCI., vol. 446, 1985, pages 93 - 104, XP009034730
- See references of WO 0192584A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0192584 A1 20011206; AT E541587 T1 20120215; AU 2001275226 B2 20070628; AU 7522601 A 20011211; CA 2410526 A1 20011206; CA 2410526 C 20120417; EP 1292709 A1 20030319; EP 1292709 A4 20040922; EP 1292709 B1 20120118; ES 2386258 T3 20120814; JP 2003535066 A 20031125; MX PA02011891 A 20040402
DOCDB simple family (application)
US 0118101 W 20010604; AT 01941913 T 20010604; AU 2001275226 A 20010604; AU 7522601 A 20010604; CA 2410526 A 20010604; EP 01941913 A 20010604; ES 01941913 T 20010604; JP 2002500775 A 20010604; MX PA02011891 A 20010604