EP 1296681 A2 20030402 - USE OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) INHIBITORS FOR REDUCING THE NUMBER OF POSTPRANDIAL TRIGLYCERIDE-RICH LIPOPROTEIN PARTICLES (PPTRL)
Title (en)
USE OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) INHIBITORS FOR REDUCING THE NUMBER OF POSTPRANDIAL TRIGLYCERIDE-RICH LIPOPROTEIN PARTICLES (PPTRL)
Title (de)
VERWENDUNG VON MTP-INHIBITOREN ZUR SENKUNG VON PPTRL
Title (fr)
UTILISATION D'INHIBITEURS DE PROTEINE DE TRANSFERT DE TRIGLYCERIDES MICROSOMALE (MTP) POUR ABAISSER LES PARTICULES DE LIPOPROTEINE A FORTE TENEUR EN TRIGLYCERIDES POSTPRANDIAUX
Publication
Application
Priority
- DE 10030375 A 20000621
- EP 0106526 W 20010608
Abstract (en)
[origin: WO0197787A2] The invention relates to the use of inhibitors of the microsomal triglyceride transfer protein (MTP) for reducing the number of postprandial triglyceride-rich lipoprotein particles (ppTRL) or for reducing their decomposition products i.e. the cholesterol-rich "small remnant particle" (remnants). Said particles are associated with apolipoprotein B-48 (ApoB-48) and are designated as "ppTRL" in the further course of events.
IPC 1-7
IPC 8 full level
C07D 275/06 (2006.01); A61K 31/4035 (2006.01); A61K 31/404 (2006.01); A61K 31/4164 (2006.01); A61K 31/4184 (2006.01); A61K 31/427 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/5025 (2006.01); A61K 31/519 (2006.01); A61K 31/522 (2006.01); A61P 3/00 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 5/50 (2006.01); A61P 7/00 (2006.01); A61P 9/00 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 209/08 (2006.01); C07D 209/48 (2006.01); C07D 235/08 (2006.01); C07D 235/18 (2006.01); C07D 235/28 (2006.01); C07D 401/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 473/08 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61K 31/437 (2013.01 - EP US); A61P 3/00 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 5/50 (2017.12 - EP); A61P 7/00 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 0197787A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0197787 A2 20011227; WO 0197787 A3 20021114; AU 7246101 A 20020102; CA 2413277 A1 20011227; DE 10030375 A1 20020103; EP 1296681 A2 20030402; JP 2003535888 A 20031202; US 2004014748 A1 20040122; US 2006166999 A1 20060727
DOCDB simple family (application)
EP 0106526 W 20010608; AU 7246101 A 20010608; CA 2413277 A 20010608; DE 10030375 A 20000621; EP 01951571 A 20010608; JP 2002503264 A 20010608; US 31176103 A 20030512; US 38881006 A 20060324