EP 1297001 A1 20030402 - AMPHIPATHIC LINEAR PEPTIDES AND COMPOSITIONS CONTAINING SAME
Title (en)
AMPHIPATHIC LINEAR PEPTIDES AND COMPOSITIONS CONTAINING SAME
Title (de)
LINEARE, AMPHIPATHISCHE PEPTIDE UND SIE ENTHALTENDE ZUBEREITUNGEN
Title (fr)
PEPTIDES LINEAIRES AMPHIPATHIQUES ET LES COMPOSITIONS LES CONTENANT
Publication
Application
Priority
- FR 0102129 W 20010703
- FR 0008633 A 20000703
Abstract (en)
[origin: WO0202595A1] The invention concerns peptides containing or consisting of an antibiotic peptide by (i) modification of cysteine residues so that said peptide is devoid of disulphide bond, (ii) substitution of 1 to 18 and preferably of 1 to 5 amino acids, and/or permutation of at least a pair of amino acids, said substitutions and/or permutations being such that said peptide has an amphipathic character. The invention also concerns a compound formed by at least one of said peptide directly or indirectly bound to at least an active substance.
IPC 1-7
IPC 8 full level
C07H 15/252 (2006.01); A61K 31/704 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01)
CPC (source: EP US)
A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07K 7/08 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 0202595A1
Citation (examination)
EISENSTEIN D. ET AL: "The helical hydrophobic moment: a measure of the amphiphilicity of a helix", NATURE, vol. 299, 23 September 1982 (1982-09-23), pages 371 - 374, XP008045352
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0202595 A1 20020110; WO 0202595 A9 20020328; AU 7261501 A 20020114; CA 2414355 A1 20020110; EP 1297001 A1 20030402; FR 2810985 A1 20020104; FR 2810985 B1 20041224; IL 153671 A0 20030706; JP 2004517039 A 20040610; US 2003186890 A1 20031002
DOCDB simple family (application)
FR 0102129 W 20010703; AU 7261501 A 20010703; CA 2414355 A 20010703; EP 01951760 A 20010703; FR 0008633 A 20000703; IL 15367101 A 20010703; JP 2002507847 A 20010703; US 33631203 A 20030103