EP 1297843 A4 20040428 - METHOD OF PHOTOREDUCTION OF HEMOGLOBIN VESICLES
Title (en)
METHOD OF PHOTOREDUCTION OF HEMOGLOBIN VESICLES
Title (de)
METHODE ZUR PHOTOREDUKTION VON HÄMOGLOBIN-VESIKELN
Title (fr)
PROCEDE DE PHOTOREDUCTION DE VESICULES D'HEMOGLOBINE
Publication
Application
Priority
- JP 0009198 W 20001225
- JP 2000175611 A 20000612
Abstract (en)
[origin: US2002095108A1] Disclosed is a method and apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method comprises adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.
IPC 1-7
IPC 8 full level
A61K 9/08 (2006.01); A61K 31/045 (2006.01); A61K 31/198 (2006.01); A61K 31/525 (2006.01); A61K 31/7004 (2006.01); A61K 31/7016 (2006.01); A61K 38/16 (2006.01); A61K 38/42 (2006.01); A61K 47/10 (2006.01); A61K 47/18 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61K 47/48 (2006.01); A61M 1/36 (2006.01); A61P 7/00 (2006.01); A61P 9/00 (2006.01)
CPC (source: EP US)
A61K 31/045 (2013.01 - EP US); A61K 31/198 (2013.01 - EP US); A61K 31/525 (2013.01 - EP US); A61K 31/7004 (2013.01 - EP US); A61K 31/7016 (2013.01 - EP US); A61K 38/42 (2013.01 - EP US); A61K 47/6445 (2017.07 - EP US); A61P 7/00 (2017.12 - EP); A61P 9/00 (2017.12 - EP)
Citation (search report)
- [PX] SAKAI HIROMI ET AL: "Photoreduction of methemoglobin by irradiation in the near-ultraviolet region", BIOCHEMISTRY, vol. 39, no. 47, 28 November 2000 (2000-11-28), pages 14595 - 14602, XP002271500, ISSN: 0006-2960
- [X] EVERSE JOHANNES: "Photochemical reduction of methemoglobin and methemoglobin derivatives", 076-6879), 1994, 1994 Academic Press, Inc., 1250 Sixth Ave., San Diego, California 92101, USA; Academic Press Ltd., 14 Belgrave Square, 24-28 Oval Road, London NW1 70X, England, UK Series: Methods in Enzymology (ISSN , pages 524 - 536, XP009026646, ISBN: 0-12-182132-3
- [X] DATABASE WPI Section PQ Week 198912, Derwent World Patents Index; Class P34, AN 1989-092183, XP002271501
- [X] DATABASE WPI Section PQ Week 198615, Derwent World Patents Index; Class P34, AN 1986-100174, XP002271502 & US 4578056 A 19860325 - KING MARTIN J [US], et al
- See references of WO 0195930A1
Designated contracting state (EPC)
DE FR GB
DOCDB simple family (publication)
US 2002095108 A1 20020718; US 6916303 B2 20050712; DE 60038057 D1 20080327; DE 60038057 T2 20090219; EP 1297843 A1 20030402; EP 1297843 A4 20040428; EP 1297843 B1 20080213; JP 2001354585 A 20011225; JP 4181290 B2 20081112; WO 0195930 A1 20011220
DOCDB simple family (application)
US 7308402 A 20020212; DE 60038057 T 20001225; EP 00985867 A 20001225; JP 0009198 W 20001225; JP 2000175611 A 20000612