Global Patent Index - EP 1303281 A1

EP 1303281 A1 20030423 - METHODS OF TREATMENT

Title (en)

METHODS OF TREATMENT

Title (de)

VERFAHREN ZUR BEHANDLUNG

Title (fr)

METHODES DE TRAITEMENT

Publication

EP 1303281 A1 20030423 (EN)

Application

EP 01927076 A 20010417

Priority

  • US 0112386 W 20010417
  • US 19771700 P 20000418

Abstract (en)

[origin: WO0178734A1] The present invention provides methods which use 4-amino-azepan-3-one protease inhibitors of cathepsin L in the treatment of diseases in which cathepsin L is implicated, especially treatment or prevention of rheumatoid arthritis; treatment or preventio nof cancer metastasis; treatment or preventio of diseases requiring inhibition of tissue destruction by macrophage, particularly lung macrophage, such as asthma, chronic obstructive pulmonary disease (COPD), and emphysema; treatment or preventoin of diseases requiring, for therapy, inhibition of positive selection of CD4<+>T<-> cells by cortical thymic epithelial cells.

IPC 1-7

A61K 31/55; A61K 31/44

IPC 8 full level

A61K 31/44 (2006.01); A61K 31/55 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01)

CPC (source: EP)

A61K 31/55 (2013.01); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 35/04 (2017.12); A61P 43/00 (2017.12)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0178734 A1 20011025; AU 5356001 A 20011030; CO 5280093 A1 20030530; EP 1303281 A1 20030423; EP 1303281 A4 20060215; JP 2003531122 A 20031021

DOCDB simple family (application)

US 0112386 W 20010417; AU 5356001 A 20010417; CO 01029288 A 20010416; EP 01927076 A 20010417; JP 2001576034 A 20010417