Global Patent Index - EP 1307208 A1

EP 1307208 A1 20030507 - USE OF CO FOR TREATING INFLAMMATION OF UPPER AIRWAYS OR BRONCHI

Title (en)

USE OF CO FOR TREATING INFLAMMATION OF UPPER AIRWAYS OR BRONCHI

Title (de)

VERWENDUNG VON CO IN DER BEHANDLUNG DER ENTZÜNDUNG DER OBEREN LUFTWEGE ODER DER BRONCHIEN

Title (fr)

UTILISATION DE CO DANS LE TRAITEMENT DE L'INFLAMMATION DES VOIES AERIENNES SUPERIEURES OU DES BRONCHES

Publication

EP 1307208 A1 20030507 (FR)

Application

EP 01956632 A 20010723

Priority

  • FR 0102396 W 20010723
  • FR 0009881 A 20000727

Abstract (en)

[origin: WO0209731A1] The invention concerns the use of carbon monoxide (CO) or a carbon monoxide (CO) donor combined with at least a gas selected among nitrogen monoxide, carbon dioxide, helium, oxygen or nitrogen, and at least an active product with anti-inflammatory activity to produce a medicine for treating or preventing an acute or chronic inflammation in a human. Furthermore, the medicine may contain an additional gas selected among xenon, hydrogen, argon, neon, krypton, nitrogen oxide (N2O), carbon-containing or fluorocarbon hydrocarbons, and their mixtures. The medicine is in the form of an inhalant aerosol. The inventive medicine is designed to treat any inflammatory pathology, vasoconstriction or bronchial constriction of the upper airways or of the bronchial tree, such as asthma, mucoviscidosis, pneumopathy and bronchial pneumopathy.

IPC 1-7

A61K 33/00; A61K 45/06; A61P 11/00

IPC 8 full level

A61K 33/00 (2006.01); A61K 45/06 (2006.01); A61P 11/00 (2006.01); A61P 29/00 (2006.01)

CPC (source: EP)

A61K 33/00 (2013.01); A61K 45/06 (2013.01); A61P 11/00 (2017.12); A61P 29/00 (2017.12)

Citation (search report)

See references of WO 0209731A1

Citation (third parties)

Third party :

  • OTTERBEIN L.E.; MANTELL L.L.; CHOI A.M.K.: "Carbon monoxide provides protection against hyperoxic lung injury", AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 20, vol. 276, 1999, pages L688 - L694, XP002960664
  • OTTERBEIN L.E. ET AL: "Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway", NATURE MEDICINE, vol. 6, no. 4, April 2000 (2000-04-01), pages 422 - 428, XP002249546
  • CHAPMAN J.T. ET AL: "EXOGENOUS CARBON MONOXIDE ATTENUATES AEROALLERGEN INDUCED EOSINOPHILIC INFLAMMATION IN MICE (Abstract)", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICIN, vol. 159, no. 3, March 1999 (1999-03-01), pages A218, XP002976612
  • TAMAYO L. ET AL: "Carbon monoxide inhibits hypoxic pulmonary vasoconstriction in rats by a cGMP-independent mechanism", EUR J PHYSIOL, vol. 434, 1997, pages 698 - 704, XP002976613

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0209731 A1 20020207; AU 7855801 A 20020213; EP 1307208 A1 20030507; FR 2812197 A1 20020201; FR 2812197 B1 20030103

DOCDB simple family (application)

FR 0102396 W 20010723; AU 7855801 A 20010723; EP 01956632 A 20010723; FR 0009881 A 20000727