EP 1307543 A2 20030507 - AUTOLOGOUS CONNECTIVE TISSUES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE
Title (en)
AUTOLOGOUS CONNECTIVE TISSUES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE
Title (de)
AUTOLOGE BINDEGEWEBE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
Title (fr)
TISSUS CONJONCTIFS AUTOLOGUES, LEUR PROCEDE DE PRODUCTION ET LEUR UTILISATION
Publication
Application
Priority
- DE 0102899 W 20010730
- DE 10038700 A 20000731
Abstract (en)
[origin: WO0210351A2] The invention relates to autologous connective tissues, to methods for the production thereof, to the stabilization of the same, and to their use as grafts. The production of the tissues ensues by isolating appropriate connective tissue cells, such as cartilage cells, perichondrial cells and/or periosteal cells as well as the corresponding precursor cells, by their multiplication in vitro (tissue engineering), by embedding them in a three-dimensional matrix, implanting the same, and by stimulating them using corticosteroids. The inventive tissues are suited for use as tissue engineering grafts, in particular, as cartilage tissue and bone tissue.
IPC 1-7
IPC 8 full level
A61P 19/04 (2006.01); C12N 5/077 (2010.01); C12N 5/22 (2006.01); A61K 35/12 (2015.01)
CPC (source: EP)
A61P 19/04 (2017.12); C12N 5/0655 (2013.01); A61K 35/12 (2013.01); C12N 2501/155 (2013.01); C12N 2501/39 (2013.01)
Citation (search report)
See references of WO 0210351A2
Citation (examination)
- WO 9909149 A1 19990225 - MASSACHUSETTS INST TECHNOLOGY [US], et al
- SITTINGER M ET AL: "Encapsulation of artificial tissues in polyelectrolyte complexes: preliminary studies", BIOMATERIALS, vol. 17, 1996, pages 1049 - 1051, XP004032692
- CAO ET AL: "COMPARATIVE STUDY OF THE USE OF POLY(GLYCOLIC ACID), CALCIUM ALGINATE AND PLURONICS IN THE ENGINEERING OF AUTOLOGOUS PORCINE CARTILAGE", J. BIOMATER. SCI. POLYMER EDN., vol. 9, no. 5, 1998, pages 475 - 487
- OKA ET AL: "Immunosuppression in Organ Transplantation", JPN. J. PHARMACOL., vol. 71, 1996, pages 89 - 100
- DE SCHEERDER ET AL: "Local methylprednisolone inhibition of foreign body response to coated intracoronary stents", CORONARY ARTERY DISEASE, vol. 7, February 1996 (1996-02-01), pages 151 - 166, XP008105565
- WILLIAMS ET AL: "A comparison of the effects of topical cyclosporine and topical steroid on rabbit corneal allograft rejection", TRANSPLANTATION, vol. 39, no. 3, March 1985 (1985-03-01), pages 242 - 244, XP008105478
- Bower-Rabinowitsch K :"Interaktion und Wirkung von Dexamethason, Wachstumshormon und IGF-I auf die Proliferation und die Typ 1 IGF-Rezeptorregulation von Wachstumsfugen-Chondrozyten in-vitro"
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0210351 A2 20020207; WO 0210351 A3 20020912; DE 10038700 A1 20020221; DE 10038700 B4 20060907; EP 1307543 A2 20030507
DOCDB simple family (application)
DE 0102899 W 20010730; DE 10038700 A 20000731; EP 01964866 A 20010730