EP 1308461 A2 20030507 - Antibodies to beta-amyloids or their derivatives and use thereof
Title (en)
Antibodies to beta-amyloids or their derivatives and use thereof
Title (de)
Antikörper gegen Beta-Amyloiden oder deren Abarten, und deren Verwendungen
Title (fr)
Anticorps contre des bèta-amyloides ou leurs dérivés, et leurs utilisations
Publication
Application
Priority
- EP 94904758 A 19940124
- JP 1013293 A 19930125
- JP 1903593 A 19930205
- JP 28698593 A 19931116
- JP 33477393 A 19931228
Abstract (en)
According to this invention, antibodies which are useful and novel in that they have binding specificity to beta -amyloids or derivatives thereof, namely recognize the N-terminal, the C-terminal or central portions of the beta -amyloids, respectively, were obtained. By combining these antibodies, determination methods by which the beta -amyloids could be determined sensitively and specifically are provided. These determination methods are useful for diagnosis of diseases to which the beta -amyloids or their derivatives are related (for example, Alzheimer's disease), and the antibodies of this invention are useful for the development of preventive-therapeutic compositions for Alzheimer's disease.
IPC 1-7
IPC 8 full level
C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 5/20 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP US)
C07K 14/4711 (2013.01 - EP US); C07K 16/18 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
EP 1308461 A2 20030507; EP 1308461 A3 20040211; AT E239797 T1 20030515; DE 69432629 D1 20030612; DE 69432629 T2 20040325; DE 69432629 T3 20080117; EP 0683234 A1 19951122; EP 0683234 A4 19980311; EP 0683234 B1 20030507; EP 0683234 B2 20070606; US 5750349 A 19980512; WO 9417197 A1 19940804
DOCDB simple family (application)
EP 02027099 A 19940124; AT 94904758 T 19940124; DE 69432629 T 19940124; EP 94904758 A 19940124; JP 9400089 W 19940124; US 30280894 A 19940915