Global Patent Index - EP 1309603 A4

EP 1309603 A4 20040728 - NUCLEIC ACIDS COMPRISING REGIONS OF THE RAT PEG-3 PROMOTER AND USES THEREOF

Title (en)

NUCLEIC ACIDS COMPRISING REGIONS OF THE RAT PEG-3 PROMOTER AND USES THEREOF

Title (de)

NUKLEINSÄUREN ENTHALTEND REGIONEN DES PEG-3 PROMOTORS AUS RATTEN

Title (fr)

ACIDES NUCLEIQUES COMPRENANT DES REGIONS DU PROMOTEUR PEG-3 DU RAT ET LEURS UTILISATIONS

Publication

EP 1309603 A4 20040728 (EN)

Application

EP 01954874 A 20010720

Priority

  • US 0123099 W 20010720
  • US 62178100 A 20000721

Abstract (en)

[origin: WO0208242A1] This invention provides for an isolated nucleic acid comprising a PEG-3 promoter comprising the nucleotide sequence beginning with the guanosine (G) at position -270 and ending with the cytosine (C) at position +194 of SEQ ID NO: 1. The invention also provides for a method for identifying an agent which modulates PEG-3 promoter activity in a cell. The invention also provides for a method for treating cancer in a subject.

IPC 1-7

C07H 21/04; C12Q 1/68; C12N 5/16; G01N 33/53; A61K 31/711

IPC 8 full level

G01N 33/50 (2006.01); A61K 31/711 (2006.01); A61K 35/76 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C40B 30/04 (2006.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

A61K 48/0058 (2013.01); A61P 35/00 (2017.12); C07K 14/47 (2013.01); C40B 30/04 (2013.01); G01N 33/6845 (2013.01)

Citation (search report)

  • [X] WO 9949898 A1 19991007 - UNIV COLUMBIA [US]
  • [XY] SU ZAO-ZHONG ET AL: "Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells", ONCOGENE, vol. 19, no. 30, 13 July 2000 (2000-07-13), pages 3411 - 3421, XP002281483, ISSN: 0950-9232
  • [Y] MILAS MIRA ET AL: "Adenovirus-mediated p53 gene therapy inhibits human sarcoma tumorigenicity", CANCER GENE THERAPY, vol. 7, no. 3, March 2000 (2000-03-01), pages 422 - 429, XP002281484, ISSN: 0929-1903
  • [PX] DATABASE EMBL [online] 9 April 2001 (2001-04-09), XP002281485, retrieved from EBI Database accession no. AF351130
  • See references of WO 0208242A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0208242 A1 20020131; AU 7709401 A 20020205; CA 2416676 A1 20020131; EP 1309603 A1 20030514; EP 1309603 A4 20040728; JP 2004520006 A 20040708

DOCDB simple family (application)

US 0123099 W 20010720; AU 7709401 A 20010720; CA 2416676 A 20010720; EP 01954874 A 20010720; JP 2002514147 A 20010720