EP 1309620 A2 20030514 - COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISORDERS INVOLVING ANGIOGENESIS
Title (en)
COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISORDERS INVOLVING ANGIOGENESIS
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR DIAGNOSE UND DER BEHANDLUNG VON KRANKHEITEN, BEI DENEN DIE ANGIOGENESE EINE ROLLE SPIELT
Title (fr)
COMPOSITIONS ET PROCEDES DE DIAGNOSE ET TRAITEMENT DE MALADIES FAISANT INTERVENIR L'ANGIOGENESE
Publication
Application
Priority
- US 0119692 W 20010620
- US 21363700 P 20000623
- US 21955600 P 20000720
- US 22062400 P 20000725
- US 22066400 P 20000725
- US 0020710 W 20000728
- US 22269500 P 20000802
- US 64365700 A 20000817
- US 0023522 W 20000823
- US 0023328 W 20000824
- US 23097800 P 20000907
- US 66461000 A 20000918
- US 66535000 A 20000918
- US 24292200 P 20001024
- US 70923800 A 20001108
- US 0030952 W 20001108
- US 0030873 W 20001110
- US 0032678 W 20001201
- US 74725900 A 20001220
- US 0034956 W 20001220
- US 76760901 A 20010122
- US 79649801 A 20010228
- US 0106520 W 20010228
- US 0106666 W 20010301
- US 80270601 A 20010309
- US 80868901 A 20010314
- US 81674401 A 20010322
- US 82836601 A 20010405
- US 85420801 A 20010510
- US 85428001 A 20010510
- US 86602801 A 20010525
- US 86603401 A 20010525
- US 0117092 W 20010525
- US 87057401 A 20010530
- US 0117443 W 20010530
- US 0117800 W 20010601
Abstract (en)
[origin: WO0200690A2] Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy.In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
IPC 1-7
IPC 8 full level
A61K 38/17 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 16/46 (2006.01); C07K 19/00 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/06 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/10 (2017.12); A61P 27/02 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07K 14/47 (2013.01)
Citation (search report)
See references of WO 0200690A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0200690 A2 20020103; WO 0200690 A3 20030313; AU 2001278852 A1 20020108; CA 2412211 A1 20020103; EP 1309620 A2 20030514; JP 2004506413 A 20040304
DOCDB simple family (application)
US 0119692 W 20010620; AU 2001278852 A 20010620; CA 2412211 A 20010620; EP 01957073 A 20010620; JP 2002505812 A 20010620